Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LA59_RS14660 Genome accession   NZ_CP009467
Coordinates   3206371..3207594 (+) Length   407 a.a.
NCBI ID   WP_005446256.1    Uniprot ID   K5TX94
Organism   Vibrio harveyi strain ATCC 33843 (392 [MAV])     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3201371..3212594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA59_RS14635 (LA59_14625) ampD 3202452..3203003 (-) 552 WP_069687467.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LA59_RS14640 (LA59_14630) nadC 3203096..3203983 (+) 888 WP_005446259.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LA59_RS14650 (LA59_14640) pilA 3204248..3204652 (+) 405 WP_050936251.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LA59_RS14655 (LA59_14645) pilB 3204652..3206337 (+) 1686 WP_049535467.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LA59_RS14660 (LA59_14650) pilC 3206371..3207594 (+) 1224 WP_005446256.1 type II secretion system F family protein Machinery gene
  LA59_RS14665 (LA59_14655) pilD 3207667..3208536 (+) 870 WP_069687468.1 A24 family peptidase Machinery gene
  LA59_RS14670 (LA59_14660) coaE 3208537..3209151 (+) 615 WP_017189130.1 dephospho-CoA kinase -
  LA59_RS14675 (LA59_14665) zapD 3209179..3209919 (+) 741 WP_005446251.1 cell division protein ZapD -
  LA59_RS14680 (LA59_14670) yacG 3209982..3210176 (+) 195 WP_005446249.1 DNA gyrase inhibitor YacG -
  LA59_RS14685 (LA59_14675) rplS 3210543..3210896 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  LA59_RS14690 (LA59_14680) trmD 3210938..3211681 (-) 744 WP_005446247.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  LA59_RS14695 (LA59_14685) rimM 3211709..3212257 (-) 549 WP_005446245.1 ribosome maturation factor RimM -
  LA59_RS14700 (LA59_14690) rpsP 3212286..3212534 (-) 249 WP_004410028.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44945.20 Da        Isoelectric Point: 10.3829

>NTDB_id=129594 LA59_RS14660 WP_005446256.1 3206371..3207594(+) (pilC) [Vibrio harveyi strain ATCC 33843 (392 [MAV])]
MKTIAPQLKNYRWKGINSSGKKTSGNVLAMTEVEVRERLDAQHIKIKKLKKGSISFITKISHRVKGKDITVFTRQIATML
MTGVPIVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASTHFDPLYTDLIATGEQSGNLSQVFERLATYREK
SEQLRAKVIKALIYPAMVVLVALGVSYLMLTKVIPEFEKMFTGFGAELPAFTQMVLNLSAWTQNWGPFIGLSFVSLLISG
KIMSQRSDSFRLLTARSSLRVPILGPVLSKAAIAKFSRTLATSFSAGIPILTALKTTSKTSGNMHYQLAIEEVYRDTAAG
MPMYIAMRNCNVFPELVLQMVMIGEESGRLDDMLNKIAAIYEFEVDNTVDNLSKILEPLIIVFLGVVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=129594 LA59_RS14660 WP_005446256.1 3206371..3207594(+) (pilC) [Vibrio harveyi strain ATCC 33843 (392 [MAV])]
ATGAAAACCATCGCTCCACAACTTAAGAACTACCGTTGGAAAGGCATTAATAGCTCGGGTAAAAAAACCTCTGGTAACGT
GCTCGCAATGACAGAAGTCGAGGTAAGAGAACGCCTTGATGCTCAGCACATCAAGATAAAAAAACTCAAAAAAGGCAGTA
TTTCTTTTATCACCAAGATAAGTCATCGAGTAAAAGGCAAAGACATTACGGTGTTTACTCGTCAAATCGCCACCATGTTG
ATGACTGGCGTCCCTATTGTTCAGGCACTCAAGTTAGTTTCAGAGAACCATAAAAAAGCTGAAATGAAGTCGATTCTAAT
GAGTGTGACGCGAGCGGTAGAAGCAGGGACACCGATGTCGAAAGCCATGCGTACCGCTAGCACGCACTTTGATCCACTTT
ACACCGATTTAATAGCAACAGGTGAGCAGTCCGGTAACTTATCCCAAGTCTTTGAGCGTCTGGCAACCTACCGAGAAAAA
AGCGAGCAGTTGCGTGCAAAGGTTATTAAAGCGCTCATTTACCCGGCGATGGTGGTATTAGTAGCACTTGGGGTTTCTTA
TTTAATGCTGACAAAGGTTATTCCTGAGTTTGAAAAAATGTTTACAGGTTTTGGTGCCGAATTACCCGCCTTCACCCAGA
TGGTACTCAACCTTTCTGCTTGGACCCAAAATTGGGGTCCCTTCATTGGGCTGAGCTTTGTGAGCTTACTCATTTCTGGC
AAAATCATGTCACAACGCTCCGACTCATTTCGTCTTTTGACTGCACGGTCGAGTTTAAGAGTACCTATTTTAGGACCAGT
TTTATCCAAAGCTGCCATTGCGAAGTTTAGCCGTACTTTGGCGACCAGTTTTAGCGCAGGTATTCCTATCCTAACCGCCT
TGAAAACTACCTCAAAAACCTCTGGTAACATGCATTATCAATTGGCAATCGAAGAGGTATATCGAGATACTGCCGCTGGT
ATGCCAATGTACATTGCCATGCGTAACTGTAACGTCTTTCCAGAATTGGTATTGCAAATGGTCATGATTGGTGAAGAGTC
AGGTCGCTTAGATGACATGCTCAACAAGATAGCCGCTATTTATGAGTTCGAAGTCGATAACACCGTCGACAACCTAAGTA
AGATTTTGGAACCGTTGATCATTGTTTTTCTGGGTGTCGTTGTCGGTGGTTTGGTGACAGCAATGTACTTACCAATCTTT
AACTTGATGAGCGTATTGGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K5TX94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

98.28

100

0.983
  pilC Vibrio cholerae strain A1552

74

98.28

0.727
  pilC Acinetobacter baylyi ADP1

42.462

97.789

0.415
  pilC Pseudomonas stutzeri DSM 10701

41.414

97.297

0.403
  pilC Acinetobacter baumannii D1279779

40.447

99.017

0.4
  pilG Neisseria gonorrhoeae MS11

39.558

100

0.396
  pilC Legionella pneumophila strain ERS1305867

39.163

99.754

0.391
  pilG Neisseria meningitidis 44/76-A

38.725

100

0.388

Multiple sequence alignment