Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   GT95_RS01065 Genome accession   NZ_CP008813
Coordinates   184366..184695 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae strain C001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 179366..189695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GT95_RS01045 (GT95_01020) - 181924..182289 (+) 366 WP_000285373.1 DUF1033 family protein -
  GT95_RS01055 (GT95_01025) comYA 182461..183432 (+) 972 WP_069107363.1 competence type IV pilus ATPase ComGA Machinery gene
  GT95_RS01060 (GT95_01030) comYB 183326..184369 (+) 1044 WP_228322108.1 competence type IV pilus assembly protein ComGB Machinery gene
  GT95_RS01065 (GT95_01035) comGC/cglC 184366..184695 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  GT95_RS01070 (GT95_01040) comYD 184670..185083 (+) 414 WP_017646959.1 competence type IV pilus minor pilin ComGD Machinery gene
  GT95_RS01075 (GT95_01045) comGE 185055..185354 (+) 300 WP_025195478.1 competence type IV pilus minor pilin ComGE -
  GT95_RS01080 (GT95_01050) comGF 185308..185769 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  GT95_RS01085 (GT95_01055) comGG 185747..186118 (+) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  GT95_RS01090 (GT95_01060) comYH 186233..187207 (+) 975 WP_001008568.1 class I SAM-dependent methyltransferase Machinery gene
  GT95_RS01095 (GT95_01065) - 187239..188432 (+) 1194 WP_000047537.1 acetate kinase -
  GT95_RS01100 (GT95_01070) - 188584..188790 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  GT95_RS01105 - 188849..188986 (+) 138 WP_079263416.1 hypothetical protein -
  GT95_RS01110 (GT95_01075) - 189089..189481 (+) 393 WP_001265365.1 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=124404 GT95_RS01065 WP_000793380.1 184366..184695(+) (comGC/cglC) [Streptococcus agalactiae strain C001]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=124404 GT95_RS01065 WP_000793380.1 184366..184695(+) (comGC/cglC) [Streptococcus agalactiae strain C001]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment