Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SD89_RS09305 Genome accession   NZ_CP010449
Coordinates   1879083..1880354 (-) Length   423 a.a.
NCBI ID   WP_053308675.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS322     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1874083..1885354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD89_RS09280 (SD89_09310) - 1876053..1876358 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  SD89_RS09285 (SD89_09315) ruvX 1876370..1876789 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  SD89_RS09290 (SD89_09320) - 1876786..1877055 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  SD89_RS09295 (SD89_09325) spx 1877169..1877567 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  SD89_RS09300 (SD89_09330) recA 1877858..1878994 (-) 1137 WP_023612576.1 recombinase RecA Machinery gene
  SD89_RS09305 (SD89_09335) cinA 1879083..1880354 (-) 1272 WP_053308675.1 competence/damage-inducible protein A Machinery gene
  SD89_RS09310 (SD89_09340) - 1880423..1880983 (-) 561 WP_053308676.1 DNA-3-methyladenine glycosylase I -
  SD89_RS09315 (SD89_09345) ruvA 1880993..1881589 (-) 597 WP_053308677.1 Holliday junction branch migration protein RuvA Machinery gene
  SD89_RS09320 (SD89_09350) - 1881591..1882811 (-) 1221 WP_053308678.1 MDR family MFS transporter -
  SD89_RS09325 (SD89_09355) hexB 1882822..1884804 (-) 1983 WP_053308679.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46086.86 Da        Isoelectric Point: 4.7760

>NTDB_id=121337 SD89_RS09305 WP_053308675.1 1879083..1880354(-) (cinA) [Streptococcus pyogenes strain NGAS322]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELIPLLPKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEEMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=121337 SD89_RS09305 WP_053308675.1 1879083..1880354(-) (cinA) [Streptococcus pyogenes strain NGAS322]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTCATTTTATGCGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTAATACCACTTCTGCCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACGGCCGAGGAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGCGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterProScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.504

100

0.695
  cinA Streptococcus mitis SK321

70.024

98.582

0.69
  cinA Streptococcus mitis NCTC 12261

69.544

98.582

0.686
  cinA Streptococcus pneumoniae TIGR4

68.585

98.582

0.676
  cinA Streptococcus pneumoniae R36A

68.585

98.582

0.676
  cinA Streptococcus pneumoniae Rx1

68.585

98.582

0.676
  cinA Streptococcus pneumoniae R6

68.585

98.582

0.676
  cinA Streptococcus pneumoniae D39

68.345

98.582

0.674
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

98.818

0.463