Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   DX05_RS01335 Genome accession   NZ_CP007572
Coordinates   229019..229414 (+) Length   131 a.a.
NCBI ID   WP_000282446.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS6     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 192991..269371 229019..229414 within 0


Gene organization within MGE regions


Location: 192991..269371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DX05_RS01150 (DX05_01165) - 192991..193227 (+) 237 WP_041326054.1 hypothetical protein -
  DX05_RS01155 (DX05_01170) - 193224..193574 (+) 351 WP_024053150.1 HTH domain-containing protein -
  DX05_RS01160 (DX05_01175) - 193577..193849 (+) 273 WP_041326056.1 hypothetical protein -
  DX05_RS01165 (DX05_01180) - 193846..194010 (+) 165 WP_041326058.1 hypothetical protein -
  DX05_RS12010 - 193997..194143 (+) 147 WP_181970976.1 hypothetical protein -
  DX05_RS01170 (DX05_01190) - 194145..195002 (+) 858 WP_041326060.1 primase alpha helix C-terminal domain-containing protein -
  DX05_RS01175 (DX05_01195) - 195085..196533 (+) 1449 WP_041326850.1 DNA primase family protein -
  DX05_RS01180 (DX05_01200) - 197391..197813 (+) 423 WP_225791875.1 hypothetical protein -
  DX05_RS01185 (DX05_01205) - 197973..198416 (+) 444 WP_024053143.1 DUF1492 domain-containing protein -
  DX05_RS01190 (DX05_01210) - 198464..199042 (+) 579 WP_024053142.1 hypothetical protein -
  DX05_RS01195 (DX05_01215) - 199042..199377 (+) 336 WP_041326062.1 hypothetical protein -
  DX05_RS01205 (DX05_01225) - 200156..200347 (+) 192 WP_003038349.1 type II toxin-antitoxin system HicA family toxin -
  DX05_RS01210 (DX05_01230) - 200384..200764 (+) 381 WP_041326065.1 type II toxin-antitoxin system HicB family antitoxin -
  DX05_RS01215 (DX05_01235) tyrS 201029..202288 (-) 1260 WP_041326067.1 tyrosine--tRNA ligase -
  DX05_RS01220 (DX05_01240) pbp1b 202399..204696 (+) 2298 WP_041326069.1 penicillin-binding protein PBP1B -
  DX05_RS01225 (DX05_01245) rpoB 205220..208795 (+) 3576 WP_000907191.1 DNA-directed RNA polymerase subunit beta -
  DX05_RS01230 (DX05_01250) rpoC 208912..212562 (+) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -
  DX05_RS01235 (DX05_01255) - 212676..213041 (+) 366 WP_000285374.1 DUF1033 family protein -
  DX05_RS01240 (DX05_01260) ltrA 213732..215009 (+) 1278 WP_001292556.1 group II intron reverse transcriptase/maturase -
  DX05_RS01245 (DX05_01265) - 215059..216471 (-) 1413 WP_017771557.1 IS1182 family transposase -
  DX05_RS01250 (DX05_01270) comYA 216636..217607 (+) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  DX05_RS01255 (DX05_01275) comGB 217501..218448 (+) 948 Protein_197 competence type IV pilus assembly protein ComGB -
  DX05_RS01270 (DX05_01290) comGF 219976..220431 (+) 456 WP_000793378.1 competence type IV pilus minor pilin ComGF -
  DX05_RS01275 (DX05_01295) comGG 220409..220780 (+) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG -
  DX05_RS01280 (DX05_01300) comYH 220895..221869 (+) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  DX05_RS01285 (DX05_01305) - 221901..223094 (+) 1194 WP_000047534.1 acetate kinase -
  DX05_RS01290 - 223222..223414 (+) 193 Protein_203 helix-turn-helix transcriptional regulator -
  DX05_RS11170 - 223393..223659 (+) 267 Protein_204 hypothetical protein -
  DX05_RS01295 (DX05_01315) - 223728..224393 (+) 666 WP_000008108.1 type II CAAX endopeptidase family protein -
  DX05_RS01300 (DX05_01320) proC 224414..225184 (-) 771 WP_001881026.1 pyrroline-5-carboxylate reductase -
  DX05_RS01305 (DX05_01325) pepA 225254..226321 (-) 1068 WP_001281321.1 glutamyl aminopeptidase -
  DX05_RS01310 (DX05_01330) - 226506..226745 (-) 240 WP_000660182.1 hypothetical protein -
  DX05_RS01315 (DX05_01335) - 226906..227190 (+) 285 WP_000791272.1 DUF4651 domain-containing protein -
  DX05_RS01320 (DX05_01340) - 227187..227510 (+) 324 WP_000602780.1 thioredoxin family protein -
  DX05_RS01325 (DX05_01345) ytpR 227543..228169 (+) 627 WP_000578324.1 YtpR family tRNA-binding protein -
  DX05_RS01330 (DX05_01350) - 228223..228938 (-) 716 Protein_212 methyltransferase domain-containing protein -
  DX05_RS01335 (DX05_01355) ssbA 229019..229414 (+) 396 WP_000282446.1 single-stranded DNA-binding protein Machinery gene
  DX05_RS01340 (DX05_01360) - 229538..230182 (+) 645 WP_000416614.1 HAD family hydrolase -
  DX05_RS01345 (DX05_01365) - 230209..231954 (+) 1746 WP_000930328.1 LytS/YhcK type 5TM receptor domain-containing protein -
  DX05_RS01350 (DX05_01370) - 231935..232679 (+) 745 Protein_216 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  DX05_RS01355 (DX05_01375) - 232849..233304 (+) 456 WP_000683317.1 CidA/LrgA family protein -
  DX05_RS01360 (DX05_01380) lrgB 233306..234034 (+) 729 WP_000421730.1 antiholin-like protein LrgB -
  DX05_RS01365 (DX05_01385) - 234277..235905 (+) 1629 WP_000170509.1 ABC transporter substrate-binding protein -
  DX05_RS01370 (DX05_01390) - 236018..236995 (+) 978 WP_000680645.1 ABC transporter permease -
  DX05_RS01375 (DX05_01395) - 236992..237813 (+) 822 WP_000603397.1 ABC transporter permease -
  DX05_RS01380 (DX05_01400) - 237825..238628 (+) 804 WP_000140980.1 ABC transporter ATP-binding protein -
  DX05_RS01385 (DX05_01405) - 238612..239238 (+) 627 WP_000171306.1 ABC transporter ATP-binding protein -
  DX05_RS01390 (DX05_01410) treP 239521..241551 (+) 2031 WP_000434616.1 PTS system trehalose-specific EIIBC component -
  DX05_RS01395 (DX05_01415) treC 241773..243398 (+) 1626 WP_000151015.1 alpha,alpha-phosphotrehalase -
  DX05_RS01400 (DX05_01420) - 243614..245650 (+) 2037 WP_000228186.1 BglG family transcription antiterminator -
  DX05_RS01405 (DX05_01425) - 245653..245937 (+) 285 WP_000944235.1 PTS sugar transporter subunit IIB -
  DX05_RS01410 (DX05_01430) - 245950..247305 (+) 1356 WP_000677351.1 PTS ascorbate transporter subunit IIC -
  DX05_RS01415 (DX05_01435) - 247308..248165 (+) 858 WP_000203493.1 transketolase -
  DX05_RS01420 (DX05_01440) - 248162..249091 (+) 930 WP_001203822.1 transketolase C-terminal domain-containing protein -
  DX05_RS01425 (DX05_01445) - 249200..250459 (+) 1260 WP_001203064.1 ferric reductase-like transmembrane domain-containing protein -
  DX05_RS01430 (DX05_01450) rpsO 250547..250816 (+) 270 WP_001018249.1 30S ribosomal protein S15 -
  DX05_RS01435 (DX05_01455) pnp 251197..253326 (+) 2130 WP_000043841.1 polyribonucleotide nucleotidyltransferase -
  DX05_RS01440 (DX05_01460) - 253328..254080 (+) 753 WP_000204781.1 SseB family protein -
  DX05_RS01445 (DX05_01465) cysE 254089..254673 (+) 585 WP_000539954.1 serine O-acetyltransferase -
  DX05_RS01450 (DX05_01470) - 254683..254865 (+) 183 WP_000656476.1 lipoprotein -
  DX05_RS01455 (DX05_01475) cysS 254862..256205 (+) 1344 WP_000591130.1 cysteine--tRNA ligase -
  DX05_RS01460 (DX05_01480) - 256198..256584 (+) 387 WP_000568029.1 Mini-ribonuclease 3 -
  DX05_RS01465 (DX05_01485) - 256710..258179 (+) 1470 WP_041326110.1 IS1182 family transposase -
  DX05_RS01470 (DX05_01490) rlmB 258247..259002 (+) 756 WP_000178021.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DX05_RS01475 (DX05_01495) - 258999..259517 (+) 519 WP_000716636.1 NYN domain-containing protein -
  DX05_RS01480 (DX05_01500) - 259610..260470 (+) 861 WP_000143135.1 DegV family protein -
  DX05_RS01485 (DX05_01510) - 261008..261127 (+) 120 Protein_243 helix-turn-helix domain-containing protein -
  DX05_RS01490 (DX05_01515) rplM 261352..261798 (+) 447 WP_001867156.1 50S ribosomal protein L13 -
  DX05_RS01495 (DX05_01520) rpsI 261819..262211 (+) 393 WP_000035940.1 30S ribosomal protein S9 -
  DX05_RS01500 (DX05_01525) - 262339..263493 (-) 1155 WP_000022172.1 tyrosine-type recombinase/integrase -
  DX05_RS01505 (DX05_01530) - 263562..264113 (-) 552 WP_001097380.1 helix-turn-helix transcriptional regulator -
  DX05_RS01510 (DX05_01535) - 264278..264571 (+) 294 WP_000331953.1 hypothetical protein -
  DX05_RS01515 (DX05_01540) - 264712..264993 (+) 282 WP_000134666.1 helix-turn-helix domain-containing protein -
  DX05_RS01520 (DX05_01545) - 264999..265326 (+) 328 Protein_250 replication initiator protein A -
  DX05_RS01525 (DX05_01550) - 265330..265971 (+) 642 WP_000591144.1 hypothetical protein -
  DX05_RS01535 (DX05_01560) - 266271..267146 (+) 876 WP_000421240.1 hypothetical protein -
  DX05_RS01540 (DX05_01565) - 267182..267616 (+) 435 WP_001220479.1 hypothetical protein -
  DX05_RS01545 (DX05_01570) mobV 267933..269189 (+) 1257 WP_000122836.1 MobV family relaxase -

Sequence


Protein


Download         Length: 131 a.a.        Molecular weight: 14735.78 Da        Isoelectric Point: 5.9381

>NTDB_id=121142 DX05_RS01335 WP_000282446.1 229019..229414(+) (ssbA) [Streptococcus agalactiae strain GBS6]
MYNKVIMIGRLTAKPEMVKTPTDKSVTRATVAVNRRFKGSNGEREADFINVVMWARLAETLASYGTKGSLISIDGELRTR
KYEKDGQTHYITEVLASSFQLLESRAQCAMRENNVSGDLSDLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=121142 DX05_RS01335 WP_000282446.1 229019..229414(+) (ssbA) [Streptococcus agalactiae strain GBS6]
ATGTATAATAAAGTTATTATGATTGGGCGTCTAACAGCAAAGCCTGAGATGGTAAAAACACCAACTGACAAGTCAGTGAC
ACGTGCAACTGTTGCTGTTAATAGACGCTTTAAAGGAAGTAATGGTGAGCGTGAAGCAGATTTTATTAATGTGGTTATGT
GGGCTCGTCTAGCGGAAACCCTTGCGAGCTATGGGACAAAGGGCTCTTTAATTTCAATAGATGGTGAATTGCGTACGCGC
AAGTACGAAAAGGATGGTCAAACGCACTATATCACTGAAGTATTAGCATCATCATTTCAGTTGTTAGAAAGCCGTGCCCA
ATGTGCTATGCGTGAAAATAATGTTTCTGGTGATTTGTCAGATTTAGTATTGGAAGAAGAGGAGCTCCCCTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Streptococcus mutans UA159

79.389

100

0.794

  ssbB/cilA Streptococcus pneumoniae R6

76.336

100

0.763

  ssbB/cilA Streptococcus pneumoniae Rx1

76.336

100

0.763

  ssbB/cilA Streptococcus pneumoniae D39

76.336

100

0.763

  ssbB/cilA Streptococcus pneumoniae TIGR4

75.573

100

0.756

  ssbB Streptococcus sobrinus strain NIDR 6715-7

75.573

100

0.756

  ssbB/cilA Streptococcus mitis NCTC 12261

74.809

100

0.748

  ssbB/cilA Streptococcus mitis SK321

74.809

100

0.748

  ssbB Lactococcus lactis subsp. cremoris KW2

59.649

87.023

0.519

  ssbA Bacillus subtilis subsp. subtilis str. 168

50.943

80.916

0.412

  ssb Latilactobacillus sakei subsp. sakei 23K

46.018

86.26

0.397


Multiple sequence alignment