Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   DI45_RS00660 Genome accession   NZ_CP007560
Coordinates   103837..104163 (+) Length   108 a.a.
NCBI ID   WP_012560386.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS743     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98837..109163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI45_RS00645 (DI45_00665) - 101469..101834 (+) 366 WP_002986560.1 DUF1033 family protein -
  DI45_RS00650 (DI45_00670) comYA 101927..102865 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  DI45_RS00655 (DI45_00675) comYB 102801..103835 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DI45_RS00660 (DI45_00680) comGC 103837..104163 (+) 327 WP_012560386.1 competence type IV pilus major pilin ComGC Machinery gene
  DI45_RS00665 (DI45_00685) comGD 104138..104566 (+) 429 WP_047235100.1 competence type IV pilus minor pilin ComGD -
  DI45_RS00670 (DI45_00690) comGE 104523..104807 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  DI45_RS00675 (DI45_00695) comYF 104800..105234 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  DI45_RS00680 (DI45_00700) comGG 105218..105544 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  DI45_RS00685 (DI45_00705) comYH 105642..106595 (+) 954 WP_009880357.1 class I SAM-dependent methyltransferase Machinery gene
  DI45_RS00690 (DI45_00710) - 106654..107850 (+) 1197 WP_030126459.1 acetate kinase -
  DI45_RS00695 (DI45_00715) - 108036..108344 (+) 309 Protein_91 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12377.35 Da        Isoelectric Point: 9.6760

>NTDB_id=120815 DI45_RS00660 WP_012560386.1 103837..104163(+) (comGC) [Streptococcus pyogenes strain NGAS743]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSELKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=120815 DI45_RS00660 WP_012560386.1 103837..104163(+) (comGC) [Streptococcus pyogenes strain NGAS743]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCGAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

57.843

94.444

0.546
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment