Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   STAB904_RS00645 Genome accession   NZ_CP007241
Coordinates   101607..102545 (+) Length   312 a.a.
NCBI ID   WP_038433848.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1E1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96607..107545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAB904_RS00635 (STAB904_00690) rpoC 97356..100997 (+) 3642 WP_030126920.1 DNA-directed RNA polymerase subunit beta' -
  STAB904_RS00640 (STAB904_00695) - 101149..101514 (+) 366 WP_038433847.1 DUF1033 family protein -
  STAB904_RS00645 (STAB904_00700) comYA 101607..102545 (+) 939 WP_038433848.1 competence type IV pilus ATPase ComGA Machinery gene
  STAB904_RS00650 (STAB904_00705) comYB 102481..103515 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  STAB904_RS00655 (STAB904_00710) comYC 103517..103843 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  STAB904_RS00660 (STAB904_00715) comGD 103818..104246 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  STAB904_RS00665 (STAB904_00720) comGE 104203..104487 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  STAB904_RS00670 (STAB904_00725) comYF 104480..104914 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  STAB904_RS00675 (STAB904_00730) comGG 104898..105224 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  STAB904_RS00680 (STAB904_00735) comYH 105322..106275 (+) 954 WP_038433850.1 class I SAM-dependent methyltransferase Machinery gene
  STAB904_RS00685 (STAB904_00740) - 106334..107530 (+) 1197 WP_010921803.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35117.37 Da        Isoelectric Point: 9.2934

>NTDB_id=118061 STAB904_RS00645 WP_038433848.1 101607..102545(+) (comYA) [Streptococcus pyogenes strain 1E1]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGRIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLFEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=118061 STAB904_RS00645 WP_038433848.1 101607..102545(+) (comYA) [Streptococcus pyogenes strain 1E1]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTTGTTGCAGGAAGGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.129

99.679

0.599
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60

99.359

0.596
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.199

99.679

0.58
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.199

99.679

0.58
  comGA Lactococcus lactis subsp. cremoris KW2

50.161

99.679

0.5
  comGA Latilactobacillus sakei subsp. sakei 23K

39.31

92.949

0.365

Multiple sequence alignment