Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   STAB904_RS00650 Genome accession   NZ_CP007241
Coordinates   102481..103515 (+) Length   344 a.a.
NCBI ID   WP_227868709.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1E1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97481..108515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAB904_RS00640 (STAB904_00695) - 101149..101514 (+) 366 WP_038433847.1 DUF1033 family protein -
  STAB904_RS00645 (STAB904_00700) comYA 101607..102545 (+) 939 WP_038433848.1 competence type IV pilus ATPase ComGA Machinery gene
  STAB904_RS00650 (STAB904_00705) comYB 102481..103515 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  STAB904_RS00655 (STAB904_00710) comYC 103517..103843 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  STAB904_RS00660 (STAB904_00715) comGD 103818..104246 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  STAB904_RS00665 (STAB904_00720) comGE 104203..104487 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  STAB904_RS00670 (STAB904_00725) comYF 104480..104914 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  STAB904_RS00675 (STAB904_00730) comGG 104898..105224 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  STAB904_RS00680 (STAB904_00735) comYH 105322..106275 (+) 954 WP_038433850.1 class I SAM-dependent methyltransferase Machinery gene
  STAB904_RS00685 (STAB904_00740) - 106334..107530 (+) 1197 WP_010921803.1 acetate kinase -
  STAB904_RS00690 (STAB904_00745) - 107717..108025 (+) 309 Protein_89 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39704.20 Da        Isoelectric Point: 9.7085

>NTDB_id=118062 STAB904_RS00650 WP_227868709.1 102481..103515(+) (comYB) [Streptococcus pyogenes strain 1E1]
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFVEVIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGL
GFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLN
HFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKS
SLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLV
VAVTIVMIYAAILLPIYQNMGGIF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=118062 STAB904_RS00650 WP_227868709.1 102481..103515(+) (comYB) [Streptococcus pyogenes strain 1E1]
TTGATCAGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAGTAAACATCAGCATAA
ATTCATTCAATTACTAGCTAATCTTTTATCTACAGGATTTAGCTTCGTAGAGGTTATTGCTTTTTTAAAAAGAAGCCAGT
TGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTTA
GGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTCA
ACATTACTTGAACCAAATGGCAAGGATCAGACGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTTC
TTTTTGTGATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAAC
CATTTTCCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTCA
AAGCCGCTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTATT
ATGCTAGAGAATGGGGTACGTTAATAGGTCAAGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATCC
TCACTAATGAAAGAATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCTA
CCCTTTTTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCTGAGTTGGAAATCT
ATGCCCAGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGTA
GTTGCTGTGACAATCGTCATGATTTATGCGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(28-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.982

98.547

0.532
  comYB Streptococcus mutans UA159

53.982

98.547

0.532
  comYB Streptococcus gordonii str. Challis substr. CH1

50.294

98.837

0.497
  comGB/cglB Streptococcus mitis NCTC 12261

47.917

97.674

0.468
  comGB/cglB Streptococcus mitis SK321

48.048

96.802

0.465
  comGB/cglB Streptococcus pneumoniae Rx1

45.946

96.802

0.445
  comGB/cglB Streptococcus pneumoniae D39

45.946

96.802

0.445
  comGB/cglB Streptococcus pneumoniae R6

45.946

96.802

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

45.946

96.802

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

42.769

94.477

0.404

Multiple sequence alignment