Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACLV7W_RS01685 Genome accession   NZ_OZ217346
Coordinates   346921..348177 (+) Length   418 a.a.
NCBI ID   WP_411865320.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis D22     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 341921..353177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS01660 (SMID22_03380) ndk 343536..343958 (+) 423 WP_411865315.1 nucleoside-diphosphate kinase -
  ACLV7W_RS01665 (SMID22_03390) comM 344088..344720 (+) 633 WP_411865316.1 competence protein Regulator
  ACLV7W_RS01670 (SMID22_03400) tsaE 344816..345259 (+) 444 WP_411865317.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV7W_RS01675 (SMID22_03410) - 345249..345767 (+) 519 WP_411865318.1 GNAT family N-acetyltransferase -
  ACLV7W_RS01680 (SMID22_03420) brpA 345775..346827 (+) 1053 WP_411865319.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV7W_RS01685 (SMID22_03430) cinA 346921..348177 (+) 1257 WP_411865320.1 competence/damage-inducible protein A Machinery gene
  ACLV7W_RS01690 (SMID22_03440) recA 348232..349398 (+) 1167 WP_064276728.1 recombinase RecA Machinery gene
  ACLV7W_RS01695 (SMID22_03450) - 349500..350870 (+) 1371 WP_411865321.1 MATE family efflux transporter -
  ACLV7W_RS01700 (SMID22_03460) - 350967..351683 (+) 717 WP_411865322.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ACLV7W_RS01705 (SMID22_03470) - 351861..352322 (+) 462 WP_411865323.1 MarR family winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45273.71 Da        Isoelectric Point: 4.6728

>NTDB_id=1170424 ACLV7W_RS01685 WP_411865320.1 346921..348177(+) (cinA) [Streptococcus mitis isolate S. mitis D22]
MKAEIMAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDPQTQEKLDVFFAQRPDYARTPNNERQAQLVEGATPLPNETGLAVGGILEVEGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKVSSQEEANQALDILENQI
LNRQTFEGLSLRKLCYGYGEETSLASIVVEELKRQGKTITAAESLTAGLFQARVADFSGASSIFKGGFVTYSLEEKSKML
DIPVKDLEEHGVVSEFTAQKMAEQARIKTQSDFGLSLTGVAGPDSLEGHPAGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1170424 ACLV7W_RS01685 WP_411865320.1 346921..348177(+) (cinA) [Streptococcus mitis isolate S. mitis D22]
ATGAAAGCAGAAATTATGGCTGTCGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCCCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTTTATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTGACAGGTGGTTTGGGGCCAACTGAGGACGACCTAACTAAACAAACT
CTAGCTAAATTTTTAGGTAAAGAATTAGTCTTTGATCCTCAGACGCAGGAGAAGTTGGATGTCTTTTTTGCTCAGAGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAACTTGTAGAAGGGGCGACTCCACTACCAAACGAAACAGGGT
TGGCAGTTGGAGGAATATTAGAAGTCGAAGGAGTGACCTACGTTGTCCTTCCTGGTCCGCCAAGTGAATTGAAACCCATG
GTTTTAAACCAACTTCTACCCAAGTTGATGACAGGAAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGAATTGGCGA
AAGTCAGTTGGTGACCATTTTGGCTGATTTGATTGACAATCAAACAGATCCGACCTTAGCGCCTTATGCCAAGACAGGAG
AAGTCACTCTGCGTCTGTCAACAAAGGTTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTAGAAAATCAAATC
TTGAATCGTCAAACTTTTGAAGGCCTTTCTTTACGAAAACTTTGTTATGGTTATGGGGAAGAAACTAGTTTAGCTAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACTATCACGGCTGCAGAGAGTTTGACGGCTGGTCTTTTCCAAGCTAGGG
TAGCGGATTTTTCGGGTGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAAAATGTTG
GATATTCCTGTCAAGGATTTGGAAGAGCACGGTGTGGTATCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAT
CAAGACCCAGTCTGATTTTGGCCTTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTGGAAGGACATCCAGCTGGGACAG
TCTTCATAGGCTTGGCTCAAGAGCAAGGAACTGAGGTTATCAAGGTCAATATTGGAGGCAGAAGTCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

96.89

100

0.969
  cinA Streptococcus mitis SK321

95.694

100

0.957
  cinA Streptococcus pneumoniae TIGR4

93.301

100

0.933
  cinA Streptococcus pneumoniae Rx1

93.062

100

0.931
  cinA Streptococcus pneumoniae R6

93.062

100

0.931
  cinA Streptococcus pneumoniae D39

92.823

100

0.928
  cinA Streptococcus mutans UA159

71.292

100

0.713
  cinA Streptococcus suis isolate S10

53.846

99.522

0.536
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment