Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACLV7A_RS01575 Genome accession   NZ_OZ217344
Coordinates   300494..301750 (+) Length   418 a.a.
NCBI ID   WP_411863409.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 295494..306750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS01545 - 296085..296255 (-) 171 WP_001227865.1 PhrA family quorum-sensing system peptide -
  ACLV7A_RS01550 (SMIE22_02970) - 296447..297310 (+) 864 WP_050167284.1 helix-turn-helix domain-containing protein -
  ACLV7A_RS01555 (SMIE22_02980) comM 297616..298236 (+) 621 WP_049532500.1 hypothetical protein Regulator
  ACLV7A_RS01560 (SMIE22_02990) tsaE 298435..298878 (+) 444 WP_411863408.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV7A_RS01565 (SMIE22_03000) - 298868..299386 (+) 519 WP_262081338.1 GNAT family N-acetyltransferase -
  ACLV7A_RS01570 (SMIE22_03010) brpA 299394..300410 (+) 1017 WP_173225226.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV7A_RS01575 (SMIE22_03020) cinA 300494..301750 (+) 1257 WP_411863409.1 competence/damage-inducible protein A Machinery gene
  ACLV7A_RS01580 (SMIE22_03030) recA 301805..302971 (+) 1167 WP_411863410.1 recombinase RecA Machinery gene
  ACLV7A_RS01585 (SMIE22_03040) - 303086..304456 (+) 1371 WP_411863411.1 MATE family efflux transporter -
  ACLV7A_RS01590 (SMIE22_03050) - 304832..305782 (+) 951 WP_411863412.1 N-acetylmuramoyl-L-alanine amidase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45062.31 Da        Isoelectric Point: 4.5211

>NTDB_id=1170267 ACLV7A_RS01575 WP_411863409.1 300494..301750(+) (cinA) [Streptococcus mitis isolate S. mitis E22]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLTLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDPQAQEKLDVFFAQRPDYARTPNNERQAQLVEGATPLPNETGLAVGGILEVNGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILEHQI
LDCQTFEGLSFRDLCYGYGEETSLASIVVEELKKQGKTITAAESLTAGLFQASLADFSGASSIFKGGFVTYSLEKKSNML
DIPVKDLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGYPAGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1170267 ACLV7A_RS01575 WP_411863409.1 300494..301750(+) (cinA) [Streptococcus mitis isolate S. mitis E22]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTTAATACCAATGCTCAATTTTTATCAGA
AAAACTAGCTGAGATTGGAGTGGACGTATATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGACTTTACTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATCCTCAGGCTCAGGAGAAGTTGGATGTCTTTTTTGCCCAGAGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAACTTGTAGAAGGAGCGACTCCACTGCCAAATGAAACAGGAT
TGGCTGTGGGAGGCATTTTGGAAGTCAATGGAGTGACCTACGTTGTTCTTCCAGGTCCACCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGTTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTGACGATTTTGGCTGATTTGATTGATAATCAGACCGATCCGACCTTGGCACCTTATGCCAAGACAGGAG
AGGTAACCTTGCGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATTTTGGAACATCAAATC
TTGGATTGCCAGACCTTTGAAGGACTTTCTTTCCGAGATCTTTGTTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTTAAAAAACAAGGGAAAACAATCACGGCTGCAGAGAGTTTGACGGCGGGTCTTTTCCAAGCTAGTC
TAGCAGATTTTTCTGGTGCTTCCAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGAAAAAATCAAACATGTTG
GATATTCCTGTCAAGGATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
TAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGATATCCAGCTGGGACAG
TCTTCATAGGCTTGGCTCAAGAGCAAGGAACTGAGGTTATCAAGGTGAATATTGGAGGCAGAAGTCGAGCAGATGTACGA
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

95.694

100

0.957
  cinA Streptococcus mitis NCTC 12261

95.215

100

0.952
  cinA Streptococcus pneumoniae TIGR4

93.301

100

0.933
  cinA Streptococcus pneumoniae Rx1

93.062

100

0.931
  cinA Streptococcus pneumoniae R6

93.062

100

0.931
  cinA Streptococcus pneumoniae D39

92.823

100

0.928
  cinA Streptococcus mutans UA159

72.01

100

0.72
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

100

0.462

Multiple sequence alignment