Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   ACLV7A_RS01555 Genome accession   NZ_OZ217344
Coordinates   297616..298236 (+) Length   206 a.a.
NCBI ID   WP_049532500.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 292616..303236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS01530 - 292627..292784 (-) 158 Protein_267 competence protein ComA -
  ACLV7A_RS01535 (SMIE22_02950) - 292925..293557 (-) 633 WP_411863406.1 ABC transporter ATP-binding protein -
  ACLV7A_RS01540 (SMIE22_02960) - 293559..295574 (-) 2016 WP_411863407.1 DUF1430 domain-containing protein -
  ACLV7A_RS01545 - 296085..296255 (-) 171 WP_001227865.1 PhrA family quorum-sensing system peptide -
  ACLV7A_RS01550 (SMIE22_02970) - 296447..297310 (+) 864 WP_050167284.1 helix-turn-helix domain-containing protein -
  ACLV7A_RS01555 (SMIE22_02980) comM 297616..298236 (+) 621 WP_049532500.1 hypothetical protein Regulator
  ACLV7A_RS01560 (SMIE22_02990) tsaE 298435..298878 (+) 444 WP_411863408.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV7A_RS01565 (SMIE22_03000) - 298868..299386 (+) 519 WP_262081338.1 GNAT family N-acetyltransferase -
  ACLV7A_RS01570 (SMIE22_03010) brpA 299394..300410 (+) 1017 WP_173225226.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV7A_RS01575 (SMIE22_03020) cinA 300494..301750 (+) 1257 WP_411863409.1 competence/damage-inducible protein A Machinery gene
  ACLV7A_RS01580 (SMIE22_03030) recA 301805..302971 (+) 1167 WP_411863410.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23504.63 Da        Isoelectric Point: 10.0254

>NTDB_id=1170266 ACLV7A_RS01555 WP_049532500.1 297616..298236(+) (comM) [Streptococcus mitis isolate S. mitis E22]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKQSVKLFYSILLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYMRDLLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1170266 ACLV7A_RS01555 WP_049532500.1 297616..298236(+) (comM) [Streptococcus mitis isolate S. mitis E22]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAAGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGTATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACTCGTAAGCAAGAAGTTCATAGTGTCCTAGCCAGTAAGCAGTCAGTGAAGCTTTTTTACAGTATCTTGCTCTTA
ATTAACTTGTTAGGAGCTGTTCTTGTCCTGTCAGATAACTTGTTCATTAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTTTTCTTTCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACATGCGTGATTTGC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTCTTCTTAAGAAATCCAATGACCATT
GTCTCTCTTTTGATTTATATTGGGCTGGGTTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCTGTTAAAAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGCTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

97.573

100

0.976
  comM Streptococcus pneumoniae R6

97.573

100

0.976
  comM Streptococcus pneumoniae TIGR4

97.573

100

0.976
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment