Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACLV65_RS01745 Genome accession   NZ_OZ217342
Coordinates   326466..327722 (+) Length   418 a.a.
NCBI ID   WP_411864373.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 321466..332722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS01715 - 322059..322231 (-) 173 Protein_304 PhrA family quorum-sensing system peptide -
  ACLV65_RS01720 (SMIB22_03320) - 322419..323282 (+) 864 WP_411864372.1 helix-turn-helix domain-containing protein -
  ACLV65_RS01725 (SMIB22_03330) comM 323588..324208 (+) 621 WP_050222261.1 hypothetical protein Regulator
  ACLV65_RS01730 (SMIB22_03340) tsaE 324407..324850 (+) 444 WP_000288239.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV65_RS01735 (SMIB22_03350) - 324840..325358 (+) 519 WP_261202887.1 GNAT family N-acetyltransferase -
  ACLV65_RS01740 (SMIB22_03360) brpA 325366..326382 (+) 1017 WP_000239274.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV65_RS01745 (SMIB22_03370) cinA 326466..327722 (+) 1257 WP_411864373.1 competence/damage-inducible protein A Machinery gene
  ACLV65_RS01750 (SMIB22_03380) recA 327777..328943 (+) 1167 WP_023933324.1 recombinase RecA Machinery gene
  ACLV65_RS01755 (SMIB22_03390) - 329164..330534 (+) 1371 WP_411864374.1 MATE family efflux transporter -
  ACLV65_RS01760 (SMIB22_03400) - 330910..331860 (+) 951 WP_000401885.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV65_RS01765 (SMIB22_03410) - 332231..332575 (+) 345 WP_001056000.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45137.53 Da        Isoelectric Point: 4.7700

>NTDB_id=1170099 ACLV65_RS01745 WP_411864373.1 326466..327722(+) (cinA) [Streptococcus mitis isolate S. mitis B22]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDSQAQEKLDRFFAQRPDYARTPNNERQAQIIEGATPLPNETGLAVGGMLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEKANQALDILENQI
LDCQTFEGPSLRELCYGYGEETSLASIVVEKLKRQGKTITAAESLTAGLFQATVADFSGASSIFKGGFVTYSLEEKSKML
DIPIKDLEGHGVVSEFIAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPAGTVFIGLAQEQGTEVIKVNIRGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1170099 ACLV65_RS01745 WP_411864373.1 326466..327722(+) (cinA) [Streptococcus mitis isolate S. mitis B22]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAATACCAATGCCCAGTTTTTGTCAGA
AAAACTAGCTGAGATTGGAGTGGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATTCTCAGGCCCAGGAGAAGTTAGATAGATTTTTTGCCCAGAGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTATAGAAGGGGCGACTCCACTGCCAAACGAAACAGGGT
TGGCTGTGGGAGGAATGTTGGAAGTCGATGGAGTGACCTACGTCGTCCTTCCAGGTCCACCAAGTGAATTGAAACCCATG
GTCTTGAACCAACTTCTACCTAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGTGA
GAGCCAGCTAGTTACGATTTTGGCTGATTTGATTGATAATCAAACCGATCCGACCTTGGCACCTTATGCTAAGACAGGAG
AAGTCACTCTGCGCCTGTCAACAAAGGCTAGCAGTCAAGAAAAGGCAAATCAGGCGCTGGATATTTTGGAAAATCAAATA
TTGGATTGTCAGACTTTCGAAGGCCCTTCTTTACGAGAACTTTGTTATGGTTATGGGGAAGAGACTAGTTTAGCCAGCAT
TGTGGTAGAAAAGCTGAAAAGGCAAGGGAAAACTATCACGGCTGCAGAGAGTTTGACGGCAGGGCTTTTCCAAGCCACTG
TGGCGGATTTTTCAGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCGAAGATGTTG
GATATTCCTATCAAGGATTTGGAAGGGCACGGTGTGGTGTCTGAATTTATAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACTCAATCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGGCACCCAGCTGGGACAG
TCTTTATAGGCTTGGCTCAAGAGCAAGGAACTGAGGTTATCAAGGTGAATATTAGAGGAAGAAGTCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

94.976

100

0.95
  cinA Streptococcus mitis NCTC 12261

94.258

100

0.943
  cinA Streptococcus pneumoniae TIGR4

93.78

100

0.938
  cinA Streptococcus pneumoniae Rx1

93.541

100

0.935
  cinA Streptococcus pneumoniae R6

93.541

100

0.935
  cinA Streptococcus pneumoniae D39

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.77

100

0.718
  cinA Streptococcus suis isolate S10

54.567

99.522

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

100

0.462

Multiple sequence alignment