Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACLV7Q_RS01535 Genome accession   NZ_OZ217341
Coordinates   290471..291727 (+) Length   418 a.a.
NCBI ID   WP_218757206.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 285471..296727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS01505 - 286076..286246 (-) 171 Protein_262 PhrA family quorum-sensing system peptide -
  ACLV7Q_RS01510 (SMIC22_02880) - 286433..287296 (+) 864 WP_218757210.1 helix-turn-helix domain-containing protein -
  ACLV7Q_RS01515 (SMIC22_02890) comM 287601..288221 (+) 621 WP_049532500.1 hypothetical protein Regulator
  ACLV7Q_RS01520 (SMIC22_02900) tsaE 288412..288855 (+) 444 WP_218757209.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV7Q_RS01525 (SMIC22_02910) - 288845..289363 (+) 519 WP_218757208.1 GNAT family N-acetyltransferase -
  ACLV7Q_RS01530 (SMIC22_02920) brpA 289371..290387 (+) 1017 WP_218757207.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV7Q_RS01535 (SMIC22_02930) cinA 290471..291727 (+) 1257 WP_218757206.1 competence/damage-inducible protein A Machinery gene
  ACLV7Q_RS01540 (SMIC22_02940) recA 291782..292948 (+) 1167 WP_050234077.1 recombinase RecA Machinery gene
  ACLV7Q_RS01545 (SMIC22_02950) - 293063..294433 (+) 1371 WP_218757205.1 MATE family efflux transporter -
  ACLV7Q_RS01550 (SMIC22_02960) - 294802..295752 (+) 951 WP_049524692.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV7Q_RS01555 (SMIC22_02970) - 296123..296467 (+) 345 WP_050086717.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45208.48 Da        Isoelectric Point: 4.4703

>NTDB_id=1170017 ACLV7Q_RS01535 WP_218757206.1 290471..291727(+) (cinA) [Streptococcus mitis isolate S. mitis C22]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDPQAQEKLDIFFAQRPDYARTPNNERQAQIVEGATPLPNETGLAVGGILEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEEANQVLDILENQI
LDRQTFEDLSLRELCYGYGEETRLASIVVEELKKQGKTITAAESLTAGLFQATVADFSGVSSIFKGGFVTYSLEEKSKML
DIPAKDLEEQGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPAGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1170017 ACLV7Q_RS01535 WP_218757206.1 290471..291727(+) (cinA) [Streptococcus mitis isolate S. mitis C22]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCTCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGAGTAGACGTATATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTACTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGACCAACTGAGGACGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATCCTCAGGCACAGGAGAAGTTGGATATCTTTTTTGCCCAGAGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAGGCTCAAATTGTAGAAGGAGCGACTCCACTGCCCAACGAAACAGGAC
TGGCTGTTGGAGGAATCTTAGAAGTTGATGGAGTGACCTACGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCTATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTGACGATTTTGGCTGATTTGATTGATAATCAGACCGATCCGACCTTGGCACCTTATGCCAAGACAGGAG
AGGTAACCTTGCGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAAGCGAATCAAGTGCTGGATATTTTGGAAAATCAAATC
TTGGATCGCCAGACCTTTGAAGATCTTTCTTTACGAGAACTTTGTTATGGTTATGGGGAAGAGACTAGATTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAAGCAAGGGAAAACCATCACTGCAGCCGAGAGTTTGACGGCAGGGCTTTTCCAAGCTACTG
TAGCGGATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTAACCTATAGCTTGGAGGAGAAATCAAAGATGTTG
GATATTCCTGCCAAGGATTTGGAAGAACAGGGTGTAGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAATCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGGCACCCAGCTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTGAATATTGGAGGCAGAAGTCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

97.368

100

0.974
  cinA Streptococcus mitis NCTC 12261

96.172

100

0.962
  cinA Streptococcus pneumoniae TIGR4

94.737

100

0.947
  cinA Streptococcus pneumoniae Rx1

94.498

100

0.945
  cinA Streptococcus pneumoniae R6

94.498

100

0.945
  cinA Streptococcus pneumoniae D39

94.258

100

0.943
  cinA Streptococcus mutans UA159

71.77

100

0.718
  cinA Streptococcus suis isolate S10

54.567

99.522

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

100

0.459

Multiple sequence alignment