Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACLV7H_RS04300 Genome accession   NZ_OZ217340
Coordinates   806193..806843 (+) Length   216 a.a.
NCBI ID   WP_411866452.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 801193..811843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS04285 (SORA22_08570) - 801968..804079 (+) 2112 WP_411866210.1 G5 domain-containing protein -
  ACLV7H_RS04290 (SORA22_08580) ald 804268..805380 (-) 1113 WP_411866450.1 alanine dehydrogenase -
  ACLV7H_RS04295 (SORA22_08590) - 805557..806126 (+) 570 WP_411866451.1 GNAT family N-acetyltransferase -
  ACLV7H_RS04300 (SORA22_08600) comEA/celA/cilE 806193..806843 (+) 651 WP_411866452.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACLV7H_RS04305 (SORA22_08610) comEC/celB 806827..809067 (+) 2241 WP_411866453.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACLV7H_RS04310 - 809254..809442 (+) 189 WP_045591667.1 hypothetical protein -
  ACLV7H_RS04315 (SORA22_08620) - 809475..810068 (+) 594 WP_411866454.1 ATP-binding cassette domain-containing protein -
  ACLV7H_RS04320 (SORA22_08630) - 810065..811249 (+) 1185 WP_411866455.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23276.53 Da        Isoelectric Point: 6.0745

>NTDB_id=1169954 ACLV7H_RS04300 WP_411866452.1 806193..806843(+) (comEA/celA/cilE) [Streptococcus oralis isolate S. oralis A22]
MEAIIEKIKEYKIIVICAVLGLALGAFFLLKPTSQTPVKEKNLQAEVAAVSKDSSSEKEVNKEEKEESPEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEVASQQTAYGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1169954 ACLV7H_RS04300 WP_411866452.1 806193..806843(+) (comEA/celA/cilE) [Streptococcus oralis isolate S. oralis A22]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATCTGTGCTGTTTTAGGCTTGGCCTTGGGCGCATT
TTTCCTACTAAAGCCAACTTCACAAACACCCGTCAAAGAAAAGAATTTGCAGGCTGAAGTCGCAGCTGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAACAAGGAAGAGAAGGAAGAATCTCCTGAACAAGATCTGATAACAGTAGATGTCAAAGGT
GCTGTTAAATCGCCAGGGATTTATGACTTGCCAGTAGGTAGTCGTGTCAATGATGCTGTTCAAAAGGCGGGTGGCTTGAC
AGAGCAAGCAGACAGCAAATCGCTCAATCTAGCTCAGAAAGTTAGTGATGAAGCTCTGGTTTACGTTCCAACTAAGGGAG
AAGAAGTAGCTAGTCAACAGACTGCTTATGGGACGGCCTCTTCGACGAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTTGGTGGCAAACGAGCCCAGGATATTATCGACCATCGTGAGGCAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTCTCTGGCATTGGCGCAAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

92.13

100

0.921
  comEA/celA/cilE Streptococcus mitis NCTC 12261

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae Rx1

91.667

100

0.917
  comEA/celA/cilE Streptococcus pneumoniae D39

91.667

100

0.917
  comEA/celA/cilE Streptococcus pneumoniae R6

91.667

100

0.917
  comEA/celA/cilE Streptococcus mitis SK321

87.963

100

0.88
  comEA Lactococcus lactis subsp. cremoris KW2

41.892

100

0.431
  comEA Streptococcus thermophilus LMD-9

40.952

97.222

0.398
  comEA Bacillus subtilis subsp. subtilis str. 168

38.863

97.685

0.38
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37

Multiple sequence alignment