Detailed information NTG1169955

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACLV7H_RS04305
• Genome accession: NZ_OZ217340
• Coordinates: 806827..809067 (+)
• Length: 746 a.a.
• NCBI ID: WP_411866453.1
• Uniprot ID: -
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 801827..814067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS04285 (SORA22_08570)	-	801968..804079 (+)	2112	WP_411866210.1	G5 domain-containing protein	-
ACLV7H_RS04290 (SORA22_08580)	ald	804268..805380 (-)	1113	WP_411866450.1	alanine dehydrogenase	-
ACLV7H_RS04295 (SORA22_08590)	-	805557..806126 (+)	570	WP_411866451.1	GNAT family N-acetyltransferase	-
ACLV7H_RS04300 (SORA22_08600)	comEA/celA/cilE	806193..806843 (+)	651	WP_411866452.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACLV7H_RS04305 (SORA22_08610)	comEC/celB	806827..809067 (+)	2241	WP_411866453.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACLV7H_RS04310	-	809254..809442 (+)	189	WP_045591667.1	hypothetical protein	-
ACLV7H_RS04315 (SORA22_08620)	-	809475..810068 (+)	594	WP_411866454.1	ATP-binding cassette domain-containing protein	-
ACLV7H_RS04320 (SORA22_08630)	-	810065..811249 (+)	1185	WP_411866455.1	hypothetical protein	-
ACLV7H_RS04325 (SORA22_08650)	infC	811554..812084 (+)	531	WP_411866456.1	translation initiation factor IF-3	-
ACLV7H_RS04330 (SORA22_08660)	rpmI	812117..812317 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
ACLV7H_RS04335 (SORA22_08670)	rplT	812369..812728 (+)	360	WP_411866457.1	50S ribosomal protein L20	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84594.86 Da
• Isoelectric Point: 8.8359

>NTDB_id=1169955 ACLV7H_RS04305 WP_411866453.1 806827..809067(+) (comEC/celB) [Streptococcus oralis isolate S. oralis A22]
MSQWIKNFPIPLIYLSFLLLWLYYAILGASYLALLGFVFLLVCLFFQFPWKPAGKVLAICGVFGFWFLFQTWQQSQASQN
LVDSVERVRILPDTIKVNGDSLSFRGKAEGHTFQVYYKLQSEEEKELFQTLTDLHEIELEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKSIQSMKQVSSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGIKGLDNFALTILVLFII
MPNFFLTAGGVLSCAYAFILTVTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQFNLVFEWLECIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIQAWQQKSTASNAQRTLIPYLKSRGVDKIDQLILTNTEK
EHVGDLLEVTRAFQVGEILVSKGSLTQKEFVAELQATQTKVRSVTGGENLPIFGSYLEVLSTRKMGDGSHDDSLFLYGRL
LDKHFLFTGNLKEKGEKDLLKQYSTLEVDVLKVGQHGSKTSSDPVFLEKLKPEITLISVGKNNRAKLPHQETLTRLETIN
SKIYRTDQNGAIRFKGWKSWQIESVC

Nucleotide

• Length: 2241 bp

>NTDB_id=1169955 ACLV7H_RS04305 WP_411866453.1 806827..809067(+) (comEC/celB) [Streptococcus oralis isolate S. oralis A22]
ATGTCACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
AGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTCCAATTTCCTTGGAAACCGGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAAAGTCAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAAAGGGTACGGATTTTGCCTGACACTATTAAGGTCAATGGAGATAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGTCACACCTTCCAAGTTTATTATAAACTCCAGTCCGAGGAAGAGAAAGAGCTCTTTCAGACCTTAACAGACC
TTCATGAGATTGAACTAGAAGGAAAACTTTCGGAACCCGAAGGGCAGAGGAATTTTGGTGGCTTTAACTACCAAGCCTAT
CTGAAGACTCAAGGAATTTACCAAACTTTGACTATCAAGAGTATCCAGTCAATGAAACAGGTTAGCAGTTGGGATATAGG
AGAAAATCTGTCTAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGATGCACTTTCCAGATCCTATGCGCAACTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACAGACTTTGAGGAGATGAATGAGCTCTATTCTAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGCATGCAGGTGGGCTTCTTTATGGATGCCTTTAAGAAACTCCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTAACTTATCCCTTTTCTCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTTATTCGCAGTC
TCTTGCAAAAGTTACTAGCACAACATGGTATTAAGGGCTTGGATAATTTTGCCTTGACGATCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCATACGCTTTTATCTTGACCGTGACTAGTAAAGAAGG
GGAGGGACTCAAGGCTGTTGCTAGAGAAAGTCTGGTCATTTCTTTGGGAATATTACCCATTCTATCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTGGTATTTTTACCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTGTTTACCCAGTCACTCAGTTTAACCTTGTCTTTGAGTGGTTGGAGTGTATCATTCGCTTGGT
ATCGCAGCTGGCAAGTAGGCCCCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTGTTAGTTTCATTAGCCT
TAGTCTATGACATGAGGAAAAACATTAAAAGACTAGCAGGATTTAGTCTCTTTATTGTGGGTCTCTTTTTCCTGACCAAG
CATCCACTTGAAAATGAAATTACCATGCTAGATGTTGGGCAGGGAGAAAGCATTTTTCTAAGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTGGGTGGAAAGGCAGAATCCGACAAAAAAATCCAAGCTTGGCAGCAAAAGTCGACGGCTAGCAATG
CCCAGCGAACCTTGATTCCCTATCTTAAAAGTCGTGGAGTAGACAAGATTGACCAGCTGATTTTGACCAACACAGAGAAA
GAGCATGTTGGAGATTTACTAGAGGTGACCAGGGCTTTCCAAGTCGGGGAGATTTTAGTATCAAAAGGAAGTTTGACACA
GAAAGAATTTGTGGCAGAACTACAAGCGACTCAAACCAAGGTACGCAGTGTGACAGGGGGGGAGAATTTACCGATTTTTG
GCAGTTACTTAGAAGTCCTATCTACAAGGAAGATGGGAGATGGAAGTCATGATGATTCTCTTTTTCTTTATGGGAGGCTT
TTGGATAAGCACTTTCTCTTTACTGGAAACTTGAAGGAGAAGGGAGAAAAGGATCTTCTAAAGCAATACTCTACCTTAGA
GGTGGATGTCTTAAAAGTCGGTCAACATGGTTCTAAAACCTCATCAGATCCAGTTTTCCTAGAAAAACTCAAACCAGAAA
TTACTCTCATTTCAGTTGGAAAGAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACACGACTAGAAACCATCAAT
AGTAAAATTTACCGAACTGACCAGAACGGAGCTATTCGCTTTAAAGGTTGGAAAAGTTGGCAAATCGAAAGTGTTTGTTA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	87.383	99.866	0.873
comEC/celB	Streptococcus mitis NCTC 12261	87.114	99.866	0.87
comEC/celB	Streptococcus pneumoniae TIGR4	86.577	99.866	0.865
comEC/celB	Streptococcus pneumoniae Rx1	86.04	99.866	0.859
comEC/celB	Streptococcus pneumoniae D39	86.04	99.866	0.859
comEC/celB	Streptococcus pneumoniae R6	86.04	99.866	0.859
comEC	Lactococcus lactis subsp. cremoris KW2	44.324	99.196	0.44