Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   QOY19_RS01145 Genome accession   NZ_OX595791
Coordinates   199146..199475 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae isolate MRI Z2-270     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194146..204475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOY19_RS01130 - 196703..197068 (+) 366 WP_000285373.1 DUF1033 family protein -
  QOY19_RS01135 comYA 197241..198212 (+) 972 WP_001933355.1 competence type IV pilus ATPase ComGA Machinery gene
  QOY19_RS01140 comYB 198106..199149 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  QOY19_RS01145 comGC/cglC 199146..199475 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  QOY19_RS01150 comYD 199450..199863 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  QOY19_RS01155 comGE 199835..200134 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  QOY19_RS01160 comGF 200088..200549 (+) 462 WP_001874812.1 competence type IV pilus minor pilin ComGF -
  QOY19_RS01165 comGG 200527..200898 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  QOY19_RS01170 comYH 201013..201987 (+) 975 WP_001008574.1 N-6 DNA methylase Machinery gene
  QOY19_RS01175 - 202019..203212 (+) 1194 WP_000047534.1 acetate kinase -
  QOY19_RS01180 - 203364..203570 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  QOY19_RS01185 - 203629..203766 (+) 138 WP_001865900.1 hypothetical protein -
  QOY19_RS01190 - 203807..204262 (+) 456 WP_000905673.1 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=1159904 QOY19_RS01145 WP_000793380.1 199146..199475(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-270]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=1159904 QOY19_RS01145 WP_000793380.1 199146..199475(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-270]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment