Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   QM552_RS10355 Genome accession   NZ_OW011623
Coordinates   2267143..2268372 (-) Length   409 a.a.
NCBI ID   WP_038011757.1    Uniprot ID   A0A127K602
Organism   Thauera humireducens strain Piv1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2262143..2273372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QM552_RS10335 (C4PIVTH_2150) aspS 2263329..2265128 (-) 1800 WP_282810207.1 aspartate--tRNA ligase -
  QM552_RS10340 (C4PIVTH_2151) - 2265197..2265820 (-) 624 WP_282810208.1 DUF502 domain-containing protein -
  QM552_RS10345 (C4PIVTH_2152) - 2265878..2266141 (-) 264 WP_048705998.1 FmdB family zinc ribbon protein -
  QM552_RS10350 (C4PIVTH_2153) pilD 2266288..2267139 (-) 852 WP_282810209.1 A24 family peptidase Machinery gene
  QM552_RS10355 (C4PIVTH_2154) pilC 2267143..2268372 (-) 1230 WP_038011757.1 type II secretion system F family protein Machinery gene
  QM552_RS10360 (C4PIVTH_2155) pilB 2268393..2270105 (-) 1713 WP_004261084.1 type IV-A pilus assembly ATPase PilB Machinery gene
  QM552_RS10365 (C4PIVTH_2156) - 2270223..2271053 (-) 831 WP_282810210.1 inner membrane protein YpjD -
  QM552_RS10370 (C4PIVTH_2157) ffh 2271105..2272475 (+) 1371 WP_282810211.1 signal recognition particle protein -
  QM552_RS10375 (C4PIVTH_2158) - 2272489..2273265 (+) 777 WP_048705991.1 EI24 domain-containing protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44150.15 Da        Isoelectric Point: 9.9581

>NTDB_id=1152202 QM552_RS10355 WP_038011757.1 2267143..2268372(-) (pilC) [Thauera humireducens strain Piv1]
MATASRAMRPAGPQEDLYNWEGKDKSGKIVRGEIRASGDAVVKAMLRRQGILVTKVKKQKLSRGGKISEKDIALFTRQLA
TMMKSGVPLLQAFDIGIKGSGNPALARLLNEVRNDVETGSSLSQAFAKHPVHFDRLFTNLVAAGEQAGILDSLLDRIATY
KEKILAIKGKIKSALFYPIAVVVVAALVISVMMLFVIPEFKSVFSGFGAELPAPTMIVIGISDFFVEFWYIVLGIPIVAI
MAISWIYKRSVAMQIAIDRLVLKLPVVGDIIRKATVARWTRTLSTMFAAGVPLVEALDSVGGASGNHIYLTATRQIQSDV
STGTSLTVAMQNANVFPTMVVQMVSIGEESGQLDAMLGKVADFFEQEVDEAVSGLSQLLEPIIMVFLGTVIGGLVIAMYL
PIFKLGSIV

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1152202 QM552_RS10355 WP_038011757.1 2267143..2268372(-) (pilC) [Thauera humireducens strain Piv1]
ATGGCAACGGCTAGCCGCGCAATGCGCCCCGCAGGCCCCCAGGAGGATCTGTACAACTGGGAAGGCAAGGACAAGTCCGG
CAAGATCGTGCGCGGCGAGATCAGGGCTTCCGGTGACGCGGTCGTCAAGGCCATGCTCCGCCGCCAGGGCATCCTGGTCA
CCAAGGTCAAGAAACAGAAGCTGTCGCGTGGCGGCAAGATCAGCGAGAAGGACATCGCGCTCTTCACCCGCCAGCTGGCG
ACAATGATGAAATCGGGCGTGCCGCTGCTTCAGGCCTTCGACATCGGCATCAAGGGTTCTGGCAACCCTGCGCTGGCACG
CCTGCTGAACGAAGTCCGGAACGACGTCGAAACCGGCTCGAGCCTGTCGCAGGCCTTCGCCAAGCACCCCGTGCATTTCG
ATCGTCTGTTCACCAACCTGGTCGCCGCCGGCGAACAGGCCGGCATCCTGGACAGCCTGCTGGACCGGATCGCCACCTAC
AAGGAAAAGATCCTTGCCATCAAGGGCAAGATCAAGTCGGCGCTGTTCTATCCGATCGCGGTCGTCGTGGTGGCCGCACT
GGTGATCTCGGTGATGATGCTGTTCGTCATTCCCGAGTTCAAGAGCGTCTTCTCCGGCTTCGGCGCCGAACTGCCGGCGC
CGACCATGATCGTCATCGGAATTTCCGACTTCTTTGTCGAGTTCTGGTACATCGTGCTCGGCATCCCCATTGTCGCGATC
ATGGCCATCAGCTGGATCTACAAACGCTCCGTCGCCATGCAGATCGCGATCGATCGCCTCGTACTCAAGCTGCCCGTCGT
CGGCGACATCATCCGCAAGGCGACGGTGGCACGCTGGACCCGTACGCTGTCGACCATGTTCGCAGCCGGCGTCCCCCTTG
TCGAAGCGCTGGATTCGGTCGGCGGCGCCTCCGGCAACCACATCTATCTGACGGCCACCCGCCAGATCCAGAGCGACGTG
AGCACCGGCACGAGCCTGACCGTCGCCATGCAGAACGCCAACGTGTTCCCGACCATGGTGGTGCAGATGGTGTCGATCGG
CGAGGAGTCCGGTCAGCTGGATGCCATGCTCGGCAAGGTGGCGGACTTCTTCGAGCAGGAAGTCGACGAGGCCGTGTCCG
GGCTGTCGCAGCTGCTCGAGCCGATCATCATGGTCTTCCTCGGCACCGTTATCGGCGGCCTGGTGATTGCGATGTACCTT
CCGATCTTCAAGCTCGGCTCGATCGTCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(279-401)

Type II secretion system (T2SS), protein F (T2SSF)

(75-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A127K602

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

52.632

97.555

0.513
  pilC Legionella pneumophila strain ERS1305867

52.764

97.311

0.513
  pilG Neisseria gonorrhoeae MS11

50.126

97.066

0.487
  pilG Neisseria meningitidis 44/76-A

49.874

97.066

0.484
  pilC Acinetobacter baylyi ADP1

48.492

97.311

0.472
  pilC Acinetobacter baumannii D1279779

47.859

97.066

0.465
  pilC Vibrio campbellii strain DS40M4

41.523

99.511

0.413
  pilC Vibrio cholerae strain A1552

41.667

96.822

0.403
  pilC Thermus thermophilus HB27

39.152

98.044

0.384

Multiple sequence alignment