Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   W903_RS01125 Genome accession   NZ_CP006910
Coordinates   191223..191552 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae CNCTC 10/84     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 186223..196552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  W903_RS01110 (W903_0226) - 188781..189146 (+) 366 WP_000285373.1 DUF1033 family protein -
  W903_RS01115 (W903_0227) comYA 189318..190289 (+) 972 WP_000250801.1 competence type IV pilus ATPase ComGA Machinery gene
  W903_RS01120 (W903_0228) comYB 190183..191226 (+) 1044 WP_228313184.1 competence type IV pilus assembly protein ComGB Machinery gene
  W903_RS01125 (W903_0229) comGC/cglC 191223..191552 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  W903_RS01130 (W903_0230) comYD 191527..191940 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  W903_RS01135 (W903_0231) comGE 191912..192211 (+) 300 WP_038406052.1 competence type IV pilus minor pilin ComGE -
  W903_RS01140 (W903_0232) comGF 192165..192626 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  W903_RS01145 (W903_0233) comGG 192604..192975 (+) 372 WP_000601105.1 competence type IV pilus minor pilin ComGG -
  W903_RS01150 (W903_0234) comYH 193090..194064 (+) 975 WP_001008567.1 class I SAM-dependent methyltransferase Machinery gene
  W903_RS01155 (W903_0235) - 194096..195289 (+) 1194 WP_000047534.1 acetate kinase -
  W903_RS01160 (W903_0236) - 195417..195609 (+) 193 Protein_173 helix-turn-helix transcriptional regulator -
  W903_RS10230 (W903_0237) - 195588..195854 (+) 267 Protein_174 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=114928 W903_RS01125 WP_000793380.1 191223..191552(+) (comGC/cglC) [Streptococcus agalactiae CNCTC 10/84]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=114928 W903_RS01125 WP_000793380.1 191223..191552(+) (comGC/cglC) [Streptococcus agalactiae CNCTC 10/84]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCTGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAGAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment