Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   VCBK1071_RS02605 Genome accession   NZ_LT897797
Coordinates   528736..529962 (-) Length   408 a.a.
NCBI ID   WP_101410156.1    Uniprot ID   -
Organism   Vibrio cholerae isolate Vibrio cholerae str. BC1071     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 523736..534962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VCBK1071_RS02580 (VCBK1071_00501) yacG 525945..526142 (-) 198 WP_000162865.1 DNA gyrase inhibitor YacG -
  VCBK1071_RS02590 (VCBK1071_00502) zapD 526426..527166 (-) 741 WP_076008577.1 cell division protein ZapD -
  VCBK1071_RS02595 (VCBK1071_00503) coaE 527198..527806 (-) 609 WP_033928827.1 dephospho-CoA kinase -
  VCBK1071_RS02600 (VCBK1071_00504) pilD 527803..528678 (-) 876 WP_032478479.1 prepilin peptidase Machinery gene
  VCBK1071_RS02605 (VCBK1071_00505) pilC 528736..529962 (-) 1227 WP_101410156.1 type II secretion system F family protein Machinery gene
  VCBK1071_RS02610 (VCBK1071_00506) pilB 530005..531693 (-) 1689 WP_044127953.1 type IV-A pilus assembly ATPase PilB Machinery gene
  VCBK1071_RS02615 (VCBK1071_00507) pilA 531697..532125 (-) 429 WP_101410158.1 pilin Machinery gene
  VCBK1071_RS02620 (VCBK1071_00508) nadC 532370..533260 (-) 891 WP_101410160.1 carboxylating nicotinate-nucleotide diphosphorylase -
  VCBK1071_RS02625 (VCBK1071_00509) ampD 533558..534103 (+) 546 WP_101410162.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  VCBK1071_RS02630 (VCBK1071_00510) fldB 534334..534852 (-) 519 WP_069503252.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45106.38 Da        Isoelectric Point: 10.3424

>NTDB_id=1146654 VCBK1071_RS02605 WP_101410156.1 528736..529962(-) (pilC) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
MKATQTLPLKNYRWKGINSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLVARLTHRVKSKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1146654 VCBK1071_RS02605 WP_101410156.1 528736..529962(-) (pilC) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGCCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGGGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTAGTGGCGCGCCTAACCCATCGCGTGAAAAGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCCATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATCACCAAAAGCGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAAGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAACTACGCGCCAAGGTGATTAAAGCGCTCATCTACCCCAGCATGGTTGTGTTGGTCGCGCTCGGGGTATC
TTACTTAATGCTCACCATGGTCATCCCAGAATTTGAAAGCATGTTTAAAGGCTTTGGTGCCGAGCTACCTTGGTTTACGC
AGCAAGTGCTGAAGCTCTCACACTGGGTACAGGCTTACAGTTTATGGGCATTTATCGCCATCGCCGCGGCCATTTTTGGC
CTGAAAGCGCTGCGTAAAAACTCCTTCCAGATCCGTTTGAAAACCAGTCGCTTGGGGCTGAAATTTCCGATTATTGGCAA
TGTACTCGCCAAAGCCTCCATCGCCAAATTCAGCCGCACCCTCGCCACCAGCTTTGCCGCGGGGATCCCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCCGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCAGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACGGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTGTTTCTTGGGACGGTCGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.51

100

0.995
  pilC Vibrio campbellii strain DS40M4

73.75

98.039

0.723
  pilC Acinetobacter baumannii D1279779

42.402

100

0.424
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.211

97.549

0.412
  pilC Pseudomonas stutzeri DSM 10701

42.172

97.059

0.409
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4

Multiple sequence alignment