Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   BUC38_RS08315 Genome accession   NZ_LT671674
Coordinates   1706008..1706670 (-) Length   220 a.a.
NCBI ID   WP_052503070.1    Uniprot ID   A0A0Z8KA39
Organism   Streptococcus suis strain LS9N     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1701008..1711670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS08310 comEC/celB 1703787..1706024 (-) 2238 WP_044690332.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BUC38_RS08315 comEA/celA/cilE 1706008..1706670 (-) 663 WP_052503070.1 helix-hairpin-helix domain-containing protein Machinery gene
  BUC38_RS08320 - 1706738..1707484 (-) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  BUC38_RS08325 - 1707632..1709077 (+) 1446 WP_044690333.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  BUC38_RS08335 - 1709543..1710328 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  BUC38_RS08340 - 1710341..1711270 (+) 930 WP_029187671.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23408.17 Da        Isoelectric Point: 4.1653

>NTDB_id=1146006 BUC38_RS08315 WP_052503070.1 1706008..1706670(-) (comEA/celA/cilE) [Streptococcus suis strain LS9N]
MDTIKTYIEMLKEYKWQIALPAAAGLLMATFLIFSQPAKSNQTGLTDFPQTEQTSSSSDLVEETSTEVSKEPSLLVVDVK
GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVTSTTASSAMSQEEKNTSLVN
LNTATEADLQTISGIGSKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1146006 BUC38_RS08315 WP_052503070.1 1706008..1706670(-) (comEA/celA/cilE) [Streptococcus suis strain LS9N]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCCTTGCCCGCAGCGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGTCAACCAGCCAAGTCTAATCAGACAGGTCTGACAGATTTTCCACAGACCGAACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTAAGGAGCCCAGCCTGCTGGTCGTTGATGTCAAA
GGAGCAGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTCAATGATGCAGTTGAAGCAGCTGGTGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGACTAGCACGACGGCCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTCAACACGGCGACTGAGGCGGACCTACAGACTATTTCGGGCATCGGTTCCAAGCGAGCGGCGGACATTATCGCCTATCG
TGAGGCCAATGGCGGCTTCAAATCGGTGGACGACCTTAACAATGTTTCAGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8KA39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae R6

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus mitis SK321

47.085

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.789

99.091

0.464
  comEA Streptococcus thermophilus LMD-9

58.599

71.364

0.418
  comEA Lactococcus lactis subsp. cremoris KW2

39.631

98.636

0.391
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364

Multiple sequence alignment