Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AC2117_RS17100 Genome accession   NZ_LS999521
Coordinates   3575595..3576821 (+) Length   408 a.a.
NCBI ID   WP_133975670.1    Uniprot ID   A0A446ZNX2
Organism   Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3570595..3581821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AC2117_RS17065 (AC2117_03383) rimP 3571263..3571787 (-) 525 WP_092710299.1 ribosome maturation factor RimP -
  AC2117_RS17085 (AC2117_03387) secG 3572427..3572756 (-) 330 WP_092710024.1 preprotein translocase subunit SecG -
  AC2117_RS17090 (AC2117_03388) tpiA 3572769..3573563 (-) 795 WP_133975666.1 triose-phosphate isomerase -
  AC2117_RS17095 (AC2117_03389) pilB 3573855..3575567 (+) 1713 WP_133975668.1 type IV-A pilus assembly ATPase PilB Machinery gene
  AC2117_RS17100 (AC2117_03390) pilC 3575595..3576821 (+) 1227 WP_133975670.1 type II secretion system F family protein Machinery gene
  AC2117_RS19165 (AC2117_03391) pilD 3576821..3577681 (+) 861 WP_133975672.1 prepilin peptidase Machinery gene
  AC2117_RS17110 (AC2117_03392) coaE 3577683..3578279 (+) 597 WP_133975674.1 dephospho-CoA kinase -
  AC2117_RS17115 (AC2117_03393) - 3578276..3579190 (-) 915 WP_133975676.1 DMT family transporter -
  AC2117_RS17120 (AC2117_03394) rlmB 3579226..3579975 (-) 750 WP_133975678.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  AC2117_RS17125 (AC2117_03395) - 3580078..3580404 (-) 327 WP_003654567.1 pyrimidine/purine nucleoside phosphorylase -
  AC2117_RS17130 (AC2117_03396) - 3580481..3581791 (-) 1311 WP_133975680.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45039.55 Da        Isoelectric Point: 10.0201

>NTDB_id=1143507 AC2117_RS17100 WP_133975670.1 3575595..3576821(+) (pilC) [Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117]
MTVKKAQLMPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEGLFKKKVSTLDITIFTRQLAT
MMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVEGGSTFASALRKYPQHFDKLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVVVVAVIVTIILMVKVVPVFQDLFSSFGADLPAFTQMVVNMSKWMQEYWFIMIIVIGAIIA
AFMEAKKRSKKFRNGLDKLTLKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVIYEQAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1143507 AC2117_RS17100 WP_133975670.1 3575595..3576821(+) (pilC) [Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117]
ATGACTGTCAAAAAGGCACAATTGATGCCGACTTTTGCTTATGAAGGGGTTGACCGTAAGGGCGTAAAAATTAAGGGAGA
ACTTCCGGCTAAAAATATGGCTTTAGCCAAAGTCACCCTACGCAAACAAGGGGTAACTGTCCGTAATATTCGGGAAAAGC
GTAAAAATATTCTTGAGGGTCTATTCAAGAAAAAAGTATCAACGCTTGATATCACTATTTTTACCCGACAACTTGCAACT
ATGATGAAAGCTGGTGTGCCACTGGTACAAGGCTTTGAAATTGTAGCGGAAGGTTTAGAAAACCCGGCGATGCGCGAGGT
GGTACTTGGTATTAAAGGCGAAGTTGAAGGAGGTAGTACTTTTGCCTCAGCTTTAAGAAAGTATCCCCAGCACTTCGACA
AATTGTTTTGCTCTCTTGTAGAGTCCGGCGAACAGTCTGGTGCGCTTGAAACCATGCTGGACCGTGTGGCAATTTACAAA
GAAAAAAGTGAATTGCTTAAGCAGAAAATCAAAAAAGCCATGAAATACCCTGCAACGGTTGTTGTGGTAGCAGTGATCGT
TACTATTATTTTGATGGTTAAAGTTGTTCCCGTCTTTCAAGACCTGTTTTCTTCCTTTGGCGCAGATTTGCCTGCTTTTA
CACAAATGGTTGTCAATATGTCGAAATGGATGCAGGAATACTGGTTCATTATGATTATTGTGATTGGTGCAATTATTGCT
GCTTTTATGGAAGCTAAAAAGCGCAGTAAAAAATTCCGTAATGGTTTAGACAAACTCACGCTTAAGTTGCCTATCTTTGG
TGATCTTGTTTACAAGGCGATTATTGCCCGCTACAGCCGTACTTTAGCCACCACTTTTGCAGCAGGTGTTCCGCTCATTG
ATGCACTTGAATCAACAGCAGGTGCAACCAATAATGTTATTTATGAACAAGCTGTAATGAAAATTCGTGAAGATGTTGCA
ACAGGTCAACAACTCCAATTTGCGATGCGCGTTTCAAATCGTTTTCCATCTATGGCTATACAAATGGTCGCAATTGGTGA
AGAATCTGGTGCACTAGACAGCATGCTCGATAAAGTGGCTACCTACTATGAAAATGAAGTTGATAATGCCGTTGATGGCT
TAACTTCAATGATGGAACCTTTAATTATGGCAATTTTAGGGGTACTGGTAGGCGGTCTGGTTATTGCTATGTATCTTCCA
ATTTTCCAAATGGGCTCAGTTGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A446ZNX2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

96.324

100

0.963
  pilC Acinetobacter baylyi ADP1

84.804

100

0.848
  pilC Pseudomonas stutzeri DSM 10701

61.209

97.304

0.596
  pilC Legionella pneumophila strain ERS1305867

52.84

99.265

0.525
  pilG Neisseria gonorrhoeae MS11

45.729

97.549

0.446
  pilG Neisseria meningitidis 44/76-A

45.729

97.549

0.446
  pilC Vibrio cholerae strain A1552

42.647

100

0.426
  pilC Vibrio campbellii strain DS40M4

40.831

100

0.409
  pilC Thermus thermophilus HB27

36.908

98.284

0.363

Multiple sequence alignment