Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   DQL01_RS10630 Genome accession   NZ_LS483451
Coordinates   1971632..1972648 (-) Length   338 a.a.
NCBI ID   WP_074017570.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1966632..1977648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS10590 - 1966841..1968031 (-) 1191 WP_000167766.1 acetate kinase -
  DQL01_RS10595 comYH 1968082..1969035 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  DQL01_RS10600 - 1969096..1969690 (-) 595 Protein_1996 class I SAM-dependent methyltransferase -
  DQL01_RS10605 comGG/cglG 1969827..1970240 (-) 414 WP_050114148.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL01_RS10610 comGF/cglF 1970218..1970679 (-) 462 WP_050114150.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL01_RS10615 comGE/cglE 1970642..1970944 (-) 303 WP_188109891.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL01_RS10620 comGD/cglD 1970907..1971311 (-) 405 WP_000588022.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL01_RS10625 comGC/cglC 1971304..1971630 (-) 327 WP_000738634.1 comG operon protein ComGC Machinery gene
  DQL01_RS10630 comGB/cglB 1971632..1972648 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL01_RS10635 comGA/cglA/cilD 1972596..1973537 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL01_RS10640 - 1973613..1973978 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQL01_RS10645 - 1974129..1975187 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  DQL01_RS10650 nagA 1975350..1976501 (-) 1152 WP_061753289.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38482.48 Da        Isoelectric Point: 9.6162

>NTDB_id=1142095 DQL01_RS10630 WP_074017570.1 1971632..1972648(-) (comGB/cglB) [Streptococcus pneumoniae strain 4041STDY6836166]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1142095 DQL01_RS10630 WP_074017570.1 1971632..1972648(-) (comGB/cglB) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment