Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQL01_RS10595 Genome accession   NZ_LS483451
Coordinates   1968082..1969035 (-) Length   317 a.a.
NCBI ID   WP_000345119.1    Uniprot ID   A0A0T7TMT7
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1963082..1974035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS10570 - 1963844..1964467 (-) 624 WP_000932659.1 hypothetical protein -
  DQL01_RS10575 jag 1964518..1965504 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  DQL01_RS10580 - 1965523..1966347 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  DQL01_RS10585 rnpA 1966322..1966693 (-) 372 WP_000739241.1 ribonuclease P protein component -
  DQL01_RS10590 - 1966841..1968031 (-) 1191 WP_000167766.1 acetate kinase -
  DQL01_RS10595 comYH 1968082..1969035 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  DQL01_RS10600 - 1969096..1969690 (-) 595 Protein_1996 class I SAM-dependent methyltransferase -
  DQL01_RS10605 comGG/cglG 1969827..1970240 (-) 414 WP_050114148.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL01_RS10610 comGF/cglF 1970218..1970679 (-) 462 WP_050114150.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL01_RS10615 comGE/cglE 1970642..1970944 (-) 303 WP_188109891.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL01_RS10620 comGD/cglD 1970907..1971311 (-) 405 WP_000588022.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL01_RS10625 comGC/cglC 1971304..1971630 (-) 327 WP_000738634.1 comG operon protein ComGC Machinery gene
  DQL01_RS10630 comGB/cglB 1971632..1972648 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL01_RS10635 comGA/cglA/cilD 1972596..1973537 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL01_RS10640 - 1973613..1973978 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35746.93 Da        Isoelectric Point: 4.2434

>NTDB_id=1142089 DQL01_RS10595 WP_000345119.1 1968082..1969035(-) (comYH) [Streptococcus pneumoniae strain 4041STDY6836166]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1142089 DQL01_RS10595 WP_000345119.1 1968082..1969035(-) (comYH) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCTTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T7TMT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment