Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL01_RS10035 Genome accession   NZ_LS483451
Coordinates   1869675..1870931 (-) Length   418 a.a.
NCBI ID   WP_061459622.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1864675..1875931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS12050 - 1864837..1864986 (+) 150 WP_001030863.1 hypothetical protein -
  DQL01_RS10010 - 1865128..1865307 (+) 180 WP_061822737.1 hypothetical protein -
  DQL01_RS10015 lytA 1865446..1866402 (-) 957 WP_061459619.1 N-acetylmuramoyl-L-alanine amidase LytA -
  DQL01_RS10020 - 1866778..1868148 (-) 1371 WP_061459620.1 MATE family efflux transporter -
  DQL01_RS10030 recA 1868454..1869620 (-) 1167 WP_061459621.1 recombinase RecA Machinery gene
  DQL01_RS10035 cinA 1869675..1870931 (-) 1257 WP_061459622.1 competence/damage-inducible protein A Machinery gene
  DQL01_RS10040 brpA 1871015..1872031 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  DQL01_RS10045 - 1872039..1872557 (-) 519 WP_000455530.1 GNAT family N-acetyltransferase -
  DQL01_RS10050 tsaE 1872547..1872990 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  DQL01_RS10060 comM 1873181..1873801 (-) 621 WP_111702721.1 hypothetical protein Regulator
  DQL01_RS10070 - 1874184..1875047 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  DQL01_RS12680 - 1875241..1875393 (+) 153 WP_152411221.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45043.44 Da        Isoelectric Point: 4.6064

>NTDB_id=1142082 DQL01_RS10035 WP_061459622.1 1869675..1870931(-) (cinA) [Streptococcus pneumoniae strain 4041STDY6836166]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQPFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1142082 DQL01_RS10035 WP_061459622.1 1869675..1870931(-) (cinA) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGCCTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGAATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.043

100

0.99
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

94.019

100

0.94
  cinA Streptococcus mitis NCTC 12261

93.78

100

0.938
  cinA Streptococcus mutans UA159

71.292

100

0.713
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment