Detailed information NTG1141737

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQL20_RS03450
• Genome accession: NZ_LS483444
• Coordinates: 626388..627125 (-)
• Length: 245 a.a.
• NCBI ID: WP_040803104.1
• Uniprot ID: -
• Organism: Streptococcus australis strain NCTC13166
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 621388..632125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL20_RS03430 (NCTC11371_00682)	-	622398..623171 (-)	774	WP_006596702.1	hypothetical protein	-
DQL20_RS03435 (NCTC11371_00683)	-	623175..624050 (-)	876	WP_006596701.1	ABC transporter ATP-binding protein	-
DQL20_RS03440 (NCTC11371_00684)	-	624104..624853 (-)	750	WP_006596700.1	hypothetical protein	-
DQL20_RS03445 (NCTC11371_00685)	-	625054..626391 (-)	1338	WP_006596699.1	sensor histidine kinase	-
DQL20_RS03450 (NCTC11371_00686)	comE/blpR	626388..627125 (-)	738	WP_040803104.1	response regulator transcription factor	Regulator
DQL20_RS03460 (NCTC11371_00687)	-	627566..627952 (-)	387	WP_006596697.1	VOC family protein	-
DQL20_RS03465 (NCTC11371_00688)	-	627964..628791 (-)	828	WP_006596696.1	exodeoxyribonuclease III	-
DQL20_RS03470 (NCTC11371_00689)	pbp2b	629109..631190 (+)	2082	WP_006596948.1	penicillin-binding protein PBP2B	-
DQL20_RS03475 (NCTC11371_00690)	recR	631201..631797 (+)	597	WP_006596694.1	recombination mediator RecR	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28429.44 Da
• Isoelectric Point: 6.6629

>NTDB_id=1141737 DQL20_RS03450 WP_040803104.1 626388..627125(-) (comE/blpR) [Streptococcus australis strain NCTC13166]
MLNIFVLEDDFLQQTRIETAIKKCMTDHHLKYKYLEVFGKPTQLLEAIKETGNHQFFFLDIEIKGEEKKGMEIAREIREK
DPSASIVFVTTHSEFMPVTYRYRVSALDFIDKGLNDQDYQEAISSVLIHAAENVNKTIGEDSFSFKSEHSQIQVPFSDIL
YFETSSTVHKVVLTTKKGHMEFYGKVSDIAKTDKRLYQSHRAYVVNPENVVRIDKANHIVYFENDESCFVSRLKLKGLVE
KVDKK

Nucleotide

• Length: 738 bp

>NTDB_id=1141737 DQL20_RS03450 WP_040803104.1 626388..627125(-) (comE/blpR) [Streptococcus australis strain NCTC13166]
ATGCTAAATATCTTTGTATTAGAAGATGATTTTCTACAACAAACACGTATTGAAACAGCAATCAAGAAATGTATGACAGA
TCATCATCTAAAGTATAAATACTTAGAGGTATTTGGGAAGCCAACACAATTGTTAGAGGCCATCAAAGAGACAGGAAATC
ACCAATTCTTTTTTTTAGATATTGAAATTAAAGGGGAAGAAAAAAAAGGAATGGAAATTGCGCGTGAGATTCGTGAAAAA
GATCCTAGCGCTTCAATCGTATTCGTAACGACTCACTCAGAATTCATGCCCGTTACCTATCGTTATCGTGTCTCCGCTTT
GGATTTTATTGATAAAGGCTTAAATGATCAGGATTATCAGGAAGCGATCTCATCTGTTTTGATACATGCTGCTGAGAACG
TCAATAAAACAATAGGGGAGGATTCCTTCAGCTTTAAATCAGAGCATTCTCAGATTCAAGTCCCTTTCTCAGATATTCTA
TATTTTGAGACATCTTCGACAGTTCATAAGGTCGTTTTAACAACTAAAAAAGGACACATGGAATTTTATGGTAAAGTCTC
AGATATTGCTAAAACCGACAAGCGACTTTACCAAAGTCATCGAGCTTACGTTGTAAATCCAGAGAATGTCGTTCGTATTG
ATAAAGCAAATCATATTGTTTACTTTGAAAATGATGAATCATGCTTTGTATCACGTTTAAAACTGAAGGGGCTAGTTGAA
AAGGTAGATAAAAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	57.741	97.551	0.563
comE/comE1	Streptococcus equinus JB1	49.174	98.776	0.486
comE/comE2	Streptococcus equinus JB1	40.741	99.184	0.404
comE	Streptococcus infantis strain Atu-4	36.145	100	0.367
comE/comE2	Streptococcus gordonii strain NCTC7865	36.626	99.184	0.363
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.626	99.184	0.363
comE	Streptococcus mitis SK321	35.743	100	0.363
comE	Streptococcus pneumoniae Rx1	35.743	100	0.363
comE	Streptococcus pneumoniae D39	35.743	100	0.363
comE	Streptococcus pneumoniae R6	35.743	100	0.363
comE	Streptococcus pneumoniae TIGR4	35.743	100	0.363
comE	Streptococcus mitis NCTC 12261	35.743	100	0.363