Detailed information NTG1139502

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM67_RS04025
• Genome accession: NZ_LS483383
• Coordinates: 794312..795043 (+)
• Length: 243 a.a.
• NCBI ID: WP_005590519.1
• Uniprot ID: -
• Organism: Streptococcus cristatus ATCC 51100 strain NCTC 12479
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 789312..800043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM67_RS03990 (NCTC12479_00769)	-	789796..790341 (+)	546	WP_005590527.1	DUF1697 domain-containing protein	-
DQM67_RS03995 (NCTC12479_00770)	-	790334..790816 (+)	483	WP_005590526.1	hypothetical protein	-
DQM67_RS04000 (NCTC12479_00771)	-	790880..791359 (+)	480	WP_005590525.1	hypothetical protein	-
DQM67_RS04005 (NCTC12479_00772)	-	791377..792153 (-)	777	WP_005590524.1	XRE family transcriptional regulator	-
DQM67_RS04010 (NCTC12479_00773)	-	792244..793086 (-)	843	WP_005590523.1	DegV family protein	-
DQM67_RS04015 (NCTC12479_00774)	-	793213..793785 (+)	573	WP_005590522.1	TetR/AcrR family transcriptional regulator	-
DQM67_RS04020 (NCTC12479_00775)	-	793969..794310 (+)	342	WP_005590520.1	LytTR family DNA-binding domain-containing protein	-
DQM67_RS04025 (NCTC12479_00776)	comE/blpR	794312..795043 (+)	732	WP_005590519.1	response regulator transcription factor	Regulator
DQM67_RS04030 (NCTC12479_00777)	-	795076..796410 (+)	1335	WP_005590517.1	sensor histidine kinase	-
DQM67_RS04040 (NCTC12479_00779)	-	797509..798372 (+)	864	WP_005590515.1	ABC transporter ATP-binding protein	-
DQM67_RS04045 (NCTC12479_00780)	-	798369..799529 (+)	1161	WP_005590514.1	ABC transporter permease subunit	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28794.98 Da
• Isoelectric Point: 6.1467

>NTDB_id=1139502 DQM67_RS04025 WP_005590519.1 794312..795043(+) (comE/blpR) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MKIFVLEDDLKQQAYMESTIQGILKKNGWECQFLEIYGKPDMLIDAVRERGSHQIFFLDIEIKQETQKGLEVAGKIRKLD
PYALIVFVTTHSEFMPLTFRYQVSAFDFIDKGLSEEDFIKQIERDLAYLYERKDSFQAEETFLFENSKSDFQVPFNEIYY
FETSEVPHRLVLYTKKERIEFYGQLSEITKQDKRLYRCHRSYVVNPANISQLDKIENIAYFPNGASCYVSRLKMKGLRTA
LRQ

Nucleotide

• Length: 732 bp

>NTDB_id=1139502 DQM67_RS04025 WP_005590519.1 794312..795043(+) (comE/blpR) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGAAAATTTTTGTATTAGAAGATGATCTTAAGCAACAAGCCTATATGGAGTCAACCATTCAGGGAATTTTGAAAAAGAA
CGGCTGGGAATGTCAATTTTTAGAAATCTACGGCAAGCCGGACATGCTGATTGATGCAGTAAGGGAACGGGGGAGCCATC
AGATTTTCTTTTTGGATATTGAGATTAAGCAAGAGACGCAGAAGGGACTCGAGGTGGCAGGAAAGATTCGCAAGTTGGAT
CCCTATGCTCTGATTGTATTTGTGACGACTCACTCAGAATTTATGCCCTTAACTTTTCGTTATCAGGTATCAGCTTTTGA
CTTTATTGATAAAGGCTTGTCTGAGGAGGATTTTATCAAGCAGATTGAGCGGGATCTGGCCTATCTTTATGAGAGAAAGG
ACAGTTTTCAAGCAGAGGAAACTTTTCTCTTTGAAAATTCCAAGTCGGATTTTCAGGTGCCATTTAATGAAATCTATTAT
TTTGAGACATCAGAAGTGCCTCATAGACTAGTTCTCTATACCAAGAAAGAGCGCATCGAATTTTACGGACAGCTTTCTGA
GATTACAAAGCAGGACAAGCGTCTCTATCGCTGCCATCGCTCTTATGTGGTCAATCCAGCGAATATCTCTCAGCTGGATA
AGATAGAAAACATAGCCTATTTCCCGAATGGCGCTAGTTGCTACGTATCACGCCTCAAGATGAAAGGATTACGGACAGCT
TTAAGGCAGTAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	57.438	99.588	0.572
comE/comE1	Streptococcus equinus JB1	45.455	99.588	0.453
comE/comE2	Streptococcus equinus JB1	43.568	99.177	0.432
comE/comE2	Streptococcus gordonii strain NCTC7865	37.751	100	0.387
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.751	100	0.387
comE	Streptococcus infantis strain Atu-4	36.4	100	0.374
comE	Streptococcus mitis NCTC 12261	35.6	100	0.366
comE	Streptococcus mitis SK321	35.6	100	0.366
comE	Streptococcus pneumoniae Rx1	35.6	100	0.366
comE	Streptococcus pneumoniae D39	35.6	100	0.366
comE	Streptococcus pneumoniae R6	35.6	100	0.366
comE	Streptococcus pneumoniae TIGR4	35.6	100	0.366