Detailed information NTG1138768

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM60_RS02345
• Genome accession: NZ_LS483366
• Coordinates: 450043..450777 (+)
• Length: 244 a.a.
• NCBI ID: WP_002886762.1
• Uniprot ID: A0AB37CQW6
• Organism: Streptococcus salivarius strain NCTC7366
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 445043..455777

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS02335 (NCTC7366_00474)	-	448248..449000 (+)	753	WP_111686482.1	response regulator transcription factor	-
DQM60_RS02340 (NCTC7366_00475)	-	449135..449800 (+)	666	WP_002886760.1	DUF6287 domain-containing protein	-
DQM60_RS02345 (NCTC7366_00476)	comE/blpR	450043..450777 (+)	735	WP_002886762.1	response regulator transcription factor	Regulator
DQM60_RS02350 (NCTC7366_00477)	-	450774..452093 (+)	1320	WP_045772182.1	GHKL domain-containing protein	-
DQM60_RS02355 (NCTC7366_00478)	-	452191..452757 (+)	567	WP_002886764.1	transcriptional regulator	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28602.00 Da
• Isoelectric Point: 6.3896

>NTDB_id=1138768 DQM60_RS02345 WP_002886762.1 450043..450777(+) (comE/blpR) [Streptococcus salivarius strain NCTC7366]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLDFITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKS
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRLESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLVNPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=1138768 DQM60_RS02345 WP_002886762.1 450043..450777(+) (comE/blpR) [Streptococcus salivarius strain NCTC7366]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTGGGCGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGACTTTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCCTAGACATTCAGATTAAAGACGATACTAAAAAAGGCTTGGAAGTTGCAAAGCAGATTCGCAAGAGT
GACCCCTATGCCAATATTGTTTTCTTCACGACTCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGACAAGTCTTTGGAGGGCGAGGACTTTCAAAAGCGTCTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGTTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACTTTGAGACCTCGGATATCGTCCACAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
TCAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGTCATAAGTCCTTCCTAGTTAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACGGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTACTTGAG
AGAATTAGCCTATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-242)

• Response regulator receiver domain (Response_reg) (6-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.049	100	0.52
comE/comE1	Streptococcus equinus JB1	47.28	97.951	0.463
comE/comE2	Streptococcus equinus JB1	42.562	99.18	0.422
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.86	99.59	0.377
comE/comE2	Streptococcus gordonii strain NCTC7865	37.86	99.59	0.377
comE	Streptococcus infantis strain Atu-4	37.759	98.77	0.373
comE	Streptococcus pneumoniae R6	37.344	98.77	0.369
comE	Streptococcus pneumoniae TIGR4	37.344	98.77	0.369
comE	Streptococcus pneumoniae D39	37.344	98.77	0.369
comE	Streptococcus mitis NCTC 12261	37.344	98.77	0.369
comE	Streptococcus pneumoniae Rx1	37.344	98.77	0.369
comE	Streptococcus mitis SK321	37.344	98.77	0.369