Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQL34_RS10340 Genome accession   NZ_LS483339
Coordinates   1948855..1949796 (-) Length   313 a.a.
NCBI ID   WP_014622005.1    Uniprot ID   A0A2X3UX10
Organism   Streptococcus thermophilus strain NCTC12958     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1943855..1954796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS10300 (NCTC12958_02177) - 1943931..1945124 (-) 1194 WP_084826168.1 acetate kinase -
  DQL34_RS10305 (NCTC12958_02178) comYH 1945180..1946136 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  DQL34_RS10310 (NCTC12958_02179) comGG 1946181..1946498 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  DQL34_RS10315 (NCTC12958_02180) comYF 1946476..1946913 (-) 438 WP_084825661.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL34_RS10320 (NCTC12958_02181) comGE 1946897..1947190 (-) 294 WP_100262274.1 competence type IV pilus minor pilin ComGE -
  DQL34_RS10325 (NCTC12958_02182) comYD 1947162..1947590 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL34_RS10330 (NCTC12958_02183) comYC 1947550..1947876 (-) 327 WP_023909980.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL34_RS10335 (NCTC12958_02184) comYB 1947873..1948973 (-) 1101 WP_133264040.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL34_RS10340 (NCTC12958_02185) comYA 1948855..1949796 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL34_RS10345 (NCTC12958_02186) - 1949877..1950239 (-) 363 WP_111679734.1 DUF1033 family protein -
  DQL34_RS10350 (NCTC12958_02187) rpoC 1950398..1954036 (-) 3639 WP_111679735.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=1137392 DQL34_RS10340 WP_014622005.1 1948855..1949796(-) (comYA) [Streptococcus thermophilus strain NCTC12958]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1137392 DQL34_RS10340 WP_014622005.1 1948855..1949796(-) (comYA) [Streptococcus thermophilus strain NCTC12958]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3UX10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment