Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQL34_RS10335 Genome accession   NZ_LS483339
Coordinates   1947873..1948973 (-) Length   366 a.a.
NCBI ID   WP_133264040.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1942873..1953973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS10295 (NCTC12958_02176) - 1943485..1943682 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  DQL34_RS10300 (NCTC12958_02177) - 1943931..1945124 (-) 1194 WP_084826168.1 acetate kinase -
  DQL34_RS10305 (NCTC12958_02178) comYH 1945180..1946136 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  DQL34_RS10310 (NCTC12958_02179) comGG 1946181..1946498 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  DQL34_RS10315 (NCTC12958_02180) comYF 1946476..1946913 (-) 438 WP_084825661.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL34_RS10320 (NCTC12958_02181) comGE 1946897..1947190 (-) 294 WP_100262274.1 competence type IV pilus minor pilin ComGE -
  DQL34_RS10325 (NCTC12958_02182) comYD 1947162..1947590 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL34_RS10330 (NCTC12958_02183) comYC 1947550..1947876 (-) 327 WP_023909980.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL34_RS10335 (NCTC12958_02184) comYB 1947873..1948973 (-) 1101 WP_133264040.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL34_RS10340 (NCTC12958_02185) comYA 1948855..1949796 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL34_RS10345 (NCTC12958_02186) - 1949877..1950239 (-) 363 WP_111679734.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41853.97 Da        Isoelectric Point: 10.0777

>NTDB_id=1137391 DQL34_RS10335 WP_133264040.1 1947873..1948973(-) (comYB) [Streptococcus thermophilus strain NCTC12958]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASYPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1137391 DQL34_RS10335 WP_133264040.1 1947873..1948973(-) (comYB) [Streptococcus thermophilus strain NCTC12958]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTTATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.971

93.443

0.514
  comYB Streptococcus mutans UA159

54.971

93.443

0.514
  comYB Streptococcus gordonii str. Challis substr. CH1

51.462

93.443

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

50.755

90.437

0.459
  comGB/cglB Streptococcus mitis SK321

50

90.164

0.451
  comGB/cglB Streptococcus pneumoniae Rx1

50

89.617

0.448
  comGB/cglB Streptococcus pneumoniae D39

50

89.617

0.448
  comGB/cglB Streptococcus pneumoniae R6

50

89.617

0.448
  comGB/cglB Streptococcus pneumoniae TIGR4

50

89.617

0.448
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment