Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   DQL30_RS00775 Genome accession   NZ_LS483333
Coordinates   117047..117361 (+) Length   104 a.a.
NCBI ID   WP_111713564.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12048     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112047..122361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL30_RS00760 (NCTC12048_00154) - 114679..115044 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL30_RS00765 (NCTC12048_00155) comYA 115137..116075 (+) 939 WP_111713563.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL30_RS00770 (NCTC12048_00156) comYB 116011..117045 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL30_RS00775 (NCTC12048_00157) comGC 117047..117361 (+) 315 WP_111713564.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL30_RS00780 (NCTC12048_00158) comGD 117336..117764 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQL30_RS00785 (NCTC12048_00159) comGE 117721..118005 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  DQL30_RS00790 (NCTC12048_00160) comYF 117998..118432 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL30_RS00795 (NCTC12048_00161) comGG 118416..118742 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL30_RS00800 (NCTC12048_00162) comYH 118840..119793 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  DQL30_RS00805 (NCTC12048_00163) - 119852..121048 (+) 1197 WP_010921803.1 acetate kinase -
  DQL30_RS00810 - 121235..121543 (+) 309 Protein_112 hypothetical protein -

Sequence

Protein


Download         Length: 104 a.a.        Molecular weight: 11905.69 Da        Isoelectric Point: 9.8992

>NTDB_id=1137004 DQL30_RS00775 WP_111713564.1 117047..117361(+) (comGC) [Streptococcus pyogenes strain NCTC12048]
MINQWNNLRHKKLKGFTLLEMLLVILVISVFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSI
TEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 315 bp        

>NTDB_id=1137004 DQL30_RS00775 WP_111713564.1 117047..117361(+) (comGC) [Streptococcus pyogenes strain NCTC12048]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTGTTGTTAAATTAG
TGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCAGATGGTAGTATC
ACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAGCAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-31)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

98.077

0.529
  comYC Streptococcus gordonii str. Challis substr. CH1

52.381

100

0.529
  comGC/cglC Streptococcus mitis SK321

58.696

88.462

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

57.609

88.462

0.51
  comGC/cglC Streptococcus pneumoniae TIGR4

57.609

88.462

0.51
  comGC/cglC Streptococcus pneumoniae D39

57.609

88.462

0.51
  comGC/cglC Streptococcus mitis NCTC 12261

57.609

88.462

0.51
  comGC/cglC Streptococcus pneumoniae R6

57.609

88.462

0.51
  comYC Streptococcus mutans UA159

50

92.308

0.462
  comYC Streptococcus mutans UA140

50

92.308

0.462
  comYC Streptococcus suis isolate S10

52.273

84.615

0.442

Multiple sequence alignment