Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQL30_RS00765 Genome accession   NZ_LS483333
Coordinates   115137..116075 (+) Length   312 a.a.
NCBI ID   WP_111713563.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12048     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 110137..121075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL30_RS00755 (NCTC12048_00153) rpoC 110886..114527 (+) 3642 WP_032460334.1 DNA-directed RNA polymerase subunit beta' -
  DQL30_RS00760 (NCTC12048_00154) - 114679..115044 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL30_RS00765 (NCTC12048_00155) comYA 115137..116075 (+) 939 WP_111713563.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL30_RS00770 (NCTC12048_00156) comYB 116011..117045 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL30_RS00775 (NCTC12048_00157) comGC 117047..117361 (+) 315 WP_111713564.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL30_RS00780 (NCTC12048_00158) comGD 117336..117764 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQL30_RS00785 (NCTC12048_00159) comGE 117721..118005 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  DQL30_RS00790 (NCTC12048_00160) comYF 117998..118432 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL30_RS00795 (NCTC12048_00161) comGG 118416..118742 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL30_RS00800 (NCTC12048_00162) comYH 118840..119793 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  DQL30_RS00805 (NCTC12048_00163) - 119852..121048 (+) 1197 WP_010921803.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35136.38 Da        Isoelectric Point: 8.8659

>NTDB_id=1137002 DQL30_RS00765 WP_111713563.1 115137..116075(+) (comYA) [Streptococcus pyogenes strain NCTC12048]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVDSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLFEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1137002 DQL30_RS00765 WP_111713563.1 115137..116075(+) (comYA) [Streptococcus pyogenes strain NCTC12048]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGATTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

59.807

99.679

0.596
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

59.677

99.359

0.593
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

57.878

99.679

0.577
  comGA/cglA/cilD Streptococcus pneumoniae D39

57.878

99.679

0.577
  comGA/cglA/cilD Streptococcus pneumoniae R6

57.878

99.679

0.577
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

57.878

99.679

0.577
  comGA Lactococcus lactis subsp. cremoris KW2

50.161

99.679

0.5
  comGA Latilactobacillus sakei subsp. sakei 23K

39.31

92.949

0.365

Multiple sequence alignment