Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H1W87_RS08610 Genome accession   NZ_LR822037
Coordinates   1653048..1653989 (-) Length   313 a.a.
NCBI ID   WP_180478282.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1121     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1648048..1658989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W87_RS08570 (STHERMO_1932) - 1648124..1649317 (-) 1194 WP_014608740.1 acetate kinase -
  H1W87_RS08575 (STHERMO_1933) comYH 1649373..1650329 (-) 957 WP_180478280.1 class I SAM-dependent methyltransferase Machinery gene
  H1W87_RS08580 (STHERMO_1934) comGG 1650374..1650691 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  H1W87_RS08585 (STHERMO_1935) comYF 1650669..1651106 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W87_RS08590 (STHERMO_1936) comGE 1651090..1651383 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  H1W87_RS08595 (STHERMO_1937) comGD 1651355..1651783 (-) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD -
  H1W87_RS08600 (STHERMO_1938) comYC 1651743..1652069 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W87_RS08605 (STHERMO_1939) comYB 1652066..1653166 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W87_RS08610 (STHERMO_1940) comYA 1653048..1653989 (-) 942 WP_180478282.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W87_RS08615 (STHERMO_1941) - 1654070..1654432 (-) 363 WP_011226630.1 DUF1033 family protein -
  H1W87_RS08620 (STHERMO_1942) rpoC 1654591..1658229 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35439.59 Da        Isoelectric Point: 6.3927

>NTDB_id=1131910 H1W87_RS08610 WP_180478282.1 1653048..1653989(-) (comYA) [Streptococcus thermophilus isolate STH_CIRM_1121]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQTIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1131910 H1W87_RS08610 WP_180478282.1 1653048..1653989(-) (comYA) [Streptococcus thermophilus isolate STH_CIRM_1121]
ATGGTAACAGAATTTGCTAAGGAAATGATAAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCTATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGACGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTCTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

63.578

100

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.538

99.681

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment