Detailed information NTG1131907

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1W87_RS08585
• Genome accession: NZ_LR822037
• Coordinates: 1650669..1651106 (-)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1121
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1645669..1656106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W87_RS08550 (STHERMO_1927)	-	1645727..1646389 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
H1W87_RS08555 (STHERMO_1928)	-	1646492..1646785 (-)	294	WP_232085688.1	hypothetical protein	-
H1W87_RS09875 (STHERMO_1929)	-	1647010..1647435 (-)	426	WP_111679733.1	CPBP family intramembrane glutamic endopeptidase	-
H1W87_RS08565 (STHERMO_1931)	-	1647678..1647875 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
H1W87_RS08570 (STHERMO_1932)	-	1648124..1649317 (-)	1194	WP_014608740.1	acetate kinase	-
H1W87_RS08575 (STHERMO_1933)	comYH	1649373..1650329 (-)	957	WP_180478280.1	class I SAM-dependent methyltransferase	Machinery gene
H1W87_RS08580 (STHERMO_1934)	comGG	1650374..1650691 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H1W87_RS08585 (STHERMO_1935)	comYF	1650669..1651106 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1W87_RS08590 (STHERMO_1936)	comGE	1651090..1651383 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H1W87_RS08595 (STHERMO_1937)	comGD	1651355..1651783 (-)	429	WP_253269448.1	competence type IV pilus minor pilin ComGD	-
H1W87_RS08600 (STHERMO_1938)	comYC	1651743..1652069 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1W87_RS08605 (STHERMO_1939)	comYB	1652066..1653166 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1W87_RS08610 (STHERMO_1940)	comYA	1653048..1653989 (-)	942	WP_180478282.1	competence type IV pilus ATPase ComGA	Machinery gene
H1W87_RS08615 (STHERMO_1941)	-	1654070..1654432 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=1131907 H1W87_RS08585 WP_011681686.1 1650669..1651106(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1121]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1131907 H1W87_RS08585 WP_011681686.1 1650669..1651106(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1121]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434