Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H0505_RS08540 Genome accession   NZ_LR822012
Coordinates   1654298..1655239 (-) Length   313 a.a.
NCBI ID   WP_084829888.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1649298..1660239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS08500 (STHERMO_1886) - 1649374..1650567 (-) 1194 WP_084831204.1 acetate kinase -
  H0505_RS08505 (STHERMO_1887) comYH 1650623..1651579 (-) 957 WP_084831205.1 class I SAM-dependent methyltransferase Machinery gene
  H0505_RS08510 (STHERMO_1888) comGG 1651624..1651941 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG -
  H0505_RS08515 (STHERMO_1889) comYF 1651919..1652356 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0505_RS08520 (STHERMO_1890) comGE 1652340..1652633 (-) 294 WP_082309154.1 competence type IV pilus minor pilin ComGE -
  H0505_RS08525 (STHERMO_1891) comGD 1652605..1653033 (-) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD -
  H0505_RS08530 (STHERMO_1892) comYC 1652993..1653319 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H0505_RS08535 (STHERMO_1893) comYB 1653316..1654416 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0505_RS08540 (STHERMO_1894) comYA 1654298..1655239 (-) 942 WP_084829888.1 competence type IV pilus ATPase ComGA Machinery gene
  H0505_RS08545 (STHERMO_1895) - 1655320..1655682 (-) 363 WP_011226630.1 DUF1033 family protein -
  H0505_RS08550 (STHERMO_1896) rpoC 1655841..1659479 (-) 3639 WP_084829890.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=1130758 H0505_RS08540 WP_084829888.1 1654298..1655239(-) (comYA) [Streptococcus thermophilus isolate STH_CIRM_30]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVIVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1130758 H0505_RS08540 WP_084829888.1 1654298..1655239(-) (comYA) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGGTAACAGAATTTGCTAAGGAAATGATAAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTTTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCTGAACGTCGGGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCTATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAATTGTTCTCTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.538

99.681

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

50.804

99.361

0.505
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment