Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   GPW68_RS00940 Genome accession   NZ_LR738723
Coordinates   143695..144090 (+) Length   131 a.a.
NCBI ID   WP_011921737.1    Uniprot ID   A0A0Z9FQS6
Organism   Streptococcus suis isolate GD-0088     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 125634..146566 143695..144090 within 0


Gene organization within MGE regions


Location: 125634..146566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS00830 - 125634..126059 (-) 426 WP_226319165.1 ArpU family phage packaging/lysis transcriptional regulator -
  GPW68_RS00835 - 126383..126958 (-) 576 WP_074392204.1 hypothetical protein -
  GPW68_RS11485 - 126979..127152 (-) 174 WP_171840772.1 hypothetical protein -
  GPW68_RS00840 - 127466..128902 (-) 1437 WP_156721189.1 phage/plasmid primase, P4 family -
  GPW68_RS00845 - 128965..129843 (-) 879 WP_074403919.1 primase alpha helix C-terminal domain-containing protein -
  GPW68_RS00850 - 129978..130262 (-) 285 WP_044766582.1 hypothetical protein -
  GPW68_RS00855 - 130252..130590 (-) 339 WP_074390405.1 hypothetical protein -
  GPW68_RS00865 - 130807..131250 (-) 444 WP_074390406.1 hypothetical protein -
  GPW68_RS00870 - 131722..132348 (-) 627 WP_074390407.1 Rha family transcriptional regulator -
  GPW68_RS00875 - 132365..132565 (-) 201 WP_015647585.1 helix-turn-helix transcriptional regulator -
  GPW68_RS11570 - 132751..133260 (+) 510 WP_370695883.1 helix-turn-helix domain-containing protein -
  GPW68_RS00885 - 133721..134866 (+) 1146 WP_074390408.1 tyrosine-type recombinase/integrase -
  GPW68_RS00890 comYH 134963..135916 (+) 954 WP_074389250.1 class I SAM-dependent methyltransferase Machinery gene
  GPW68_RS00895 - 135966..137153 (+) 1188 WP_074389251.1 acetate kinase -
  GPW68_RS00900 - 137468..138019 (+) 552 WP_024389479.1 folate family ECF transporter S component -
  GPW68_RS00905 - 138075..139331 (+) 1257 WP_074389253.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  GPW68_RS00910 pepA 139376..140437 (-) 1062 WP_074389254.1 glutamyl aminopeptidase -
  GPW68_RS00915 - 140584..140868 (+) 285 WP_044674517.1 DUF4651 domain-containing protein -
  GPW68_RS00920 - 140865..141185 (+) 321 WP_024386832.1 thioredoxin family protein -
  GPW68_RS00925 - 141230..142186 (+) 957 WP_044754802.1 DUF1002 domain-containing protein -
  GPW68_RS00930 ytpR 142205..142828 (+) 624 WP_074389255.1 YtpR family tRNA-binding protein -
  GPW68_RS00935 - 142861..143640 (-) 780 WP_074389256.1 DUF2785 domain-containing protein -
  GPW68_RS00940 ssbA 143695..144090 (+) 396 WP_011921737.1 single-stranded DNA-binding protein Machinery gene
  GPW68_RS11490 - 144209..144454 (-) 246 WP_074389257.1 hypothetical protein -
  GPW68_RS00950 groES 144651..144932 (+) 282 WP_074389258.1 co-chaperone GroES -
  GPW68_RS00955 groL 144944..146566 (+) 1623 WP_074389259.1 chaperonin GroEL -

Sequence


Protein


Download         Length: 131 a.a.        Molecular weight: 14868.73 Da        Isoelectric Point: 5.0026

>NTDB_id=1129535 GPW68_RS00940 WP_011921737.1 143695..144090(+) (ssbA) [Streptococcus suis isolate GD-0088]
MYNKTILIGRLTAQPELTQTPTGKNLTRVTVAVNRRFKTENGEREADFLNVIFWGKLAETLVSYGSKGSLISIDGELRTR
KYEKDGSNHYVTEILGQSFQLLESRAQRAMRENNTGDDLADLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=1129535 GPW68_RS00940 WP_011921737.1 143695..144090(+) (ssbA) [Streptococcus suis isolate GD-0088]
ATGTATAATAAAACAATTTTAATCGGTCGCTTGACGGCCCAACCTGAACTCACTCAAACGCCAACTGGCAAAAATTTGAC
TCGTGTAACAGTTGCAGTCAATCGCCGATTTAAGACAGAAAACGGTGAGCGTGAAGCAGATTTTCTTAATGTTATTTTCT
GGGGAAAACTGGCGGAAACACTTGTCTCCTATGGTAGCAAGGGTAGTCTGATTTCTATTGATGGTGAGTTGCGAACGCGA
AAATACGAAAAAGACGGCAGCAACCACTATGTGACAGAGATTTTGGGACAATCGTTCCAGTTGCTCGAAAGTCGGGCTCA
ACGTGCCATGCGTGAAAATAATACTGGTGATGACCTAGCTGACTTGGTCTTGGAAGAGGAGGAATTACCGTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0Z9FQS6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Streptococcus mutans UA159

76.336

100

0.763

  ssbB Streptococcus sobrinus strain NIDR 6715-7

75.573

100

0.756

  ssbB/cilA Streptococcus pneumoniae TIGR4

71.756

100

0.718

  ssbB/cilA Streptococcus mitis NCTC 12261

70.992

100

0.71

  ssbB/cilA Streptococcus pneumoniae Rx1

70.992

100

0.71

  ssbB/cilA Streptococcus pneumoniae D39

70.992

100

0.71

  ssbB/cilA Streptococcus pneumoniae R6

70.992

100

0.71

  ssbB/cilA Streptococcus mitis SK321

70.992

100

0.71

  ssbB Lactococcus lactis subsp. cremoris KW2

64.286

85.496

0.55

  ssb Latilactobacillus sakei subsp. sakei 23K

44.248

86.26

0.382

  ssbA Bacillus subtilis subsp. subtilis str. 168

46.226

80.916

0.374


Multiple sequence alignment