Detailed information NTG1127791

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: FGL18_RS02765
• Genome accession: NZ_LR594046
• Coordinates: 522395..523144 (+)
• Length: 249 a.a.
• NCBI ID: WP_129556053.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 517395..528144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS02735 (NCTC6403_00557)	ybeY	517711..518208 (+)	498	WP_138124978.1	rRNA maturation RNase YbeY	-
FGL18_RS02740 (NCTC6403_00558)	-	518189..518596 (+)	408	WP_003054389.1	diacylglycerol kinase	-
FGL18_RS02745 (NCTC6403_00559)	era	518717..519613 (+)	897	WP_138124980.1	GTPase Era	-
FGL18_RS02750 (NCTC6403_00560)	-	519800..520276 (+)	477	WP_138124982.1	NUDIX domain-containing protein	-
FGL18_RS02755 (NCTC6403_00561)	-	520582..520956 (+)	375	WP_242002892.1	hypothetical protein	-
FGL18_RS02760	-	521069..521991 (+)	923	Protein_480	IS30 family transposase	-
FGL18_RS02765 (NCTC6403_00564)	comE/blpR	522395..523144 (+)	750	WP_129556053.1	response regulator transcription factor	Regulator
FGL18_RS02770 (NCTC6403_00565)	-	523145..524479 (+)	1335	WP_138124984.1	GHKL domain-containing protein	-
FGL18_RS02775 (NCTC6403_00566)	-	524627..524752 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FGL18_RS02780	-	524843..526207 (-)	1365	Protein_484	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29257.56 Da
• Isoelectric Point: 5.6284

>NTDB_id=1127791 FGL18_RS02765 WP_129556053.1 522395..523144(+) (comE/blpR) [Streptococcus dysgalactiae strain NCTC6403]
MNIFVLEDDFLQQTRIEKIIYKILTDNKWEINHLEVYGKPNQLLEDISERGRHQLFFLDIDIKGEDKKGMEIAVEIRNRD
PHAVIVFVTTHSEFMPVSFQYQVSALDFIDKELPEELFSHRIEKAITYVQDNQGKTLAEDSFVFTNVKSQIQVPFSDLLY
IETSLIPHKLILYSTKQRVEFYGQLSEIVEQDDRLFQCHRSFVVNPYNISSIDRSERLVYLKGGLSCIVSRLKIRSLIKV
VEELHTKEK

Nucleotide

• Length: 750 bp

>NTDB_id=1127791 FGL18_RS02765 WP_129556053.1 522395..523144(+) (comE/blpR) [Streptococcus dysgalactiae strain NCTC6403]
ATGAATATTTTTGTCTTAGAGGACGATTTTTTACAACAAACTAGAATTGAAAAAATTATTTATAAGATTTTGACTGATAA
TAAGTGGGAGATTAACCACTTGGAAGTTTATGGTAAACCTAATCAGCTGCTTGAAGATATATCAGAGAGAGGAAGACATC
AGCTTTTTTTTCTTGACATTGACATTAAGGGAGAAGATAAAAAAGGAATGGAAATTGCTGTGGAGATTAGAAATAGAGAT
CCGCACGCAGTGATAGTTTTTGTGACCACACATTCAGAATTTATGCCGGTATCTTTTCAATACCAGGTTTCAGCTTTAGA
CTTTATTGACAAAGAGTTGCCAGAGGAGTTATTTAGTCATCGCATTGAAAAAGCTATAACTTATGTACAAGATAACCAAG
GAAAAACGTTAGCGGAGGATTCATTTGTTTTTACTAATGTAAAGTCCCAGATACAAGTCCCCTTTTCAGATTTGCTGTAT
ATTGAAACCTCACTAATTCCCCATAAACTCATTCTCTATTCTACTAAACAAAGAGTAGAATTTTATGGCCAATTATCAGA
AATTGTTGAGCAAGATGATCGATTATTTCAATGTCATCGTTCCTTTGTTGTTAATCCCTATAATATATCATCAATAGATA
GATCCGAACGGTTAGTTTATTTAAAGGGGGGATTATCTTGTATTGTTTCGAGATTGAAAATACGATCATTAATAAAAGTA
GTAGAAGAGTTGCACACTAAGGAGAAATAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-119)

• LytTr DNA-binding domain (LytTR) (150-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.328	97.992	0.542
comE/comE1	Streptococcus equinus JB1	42.857	95.582	0.41
comE/comE2	Streptococcus gordonii strain NCTC7865	40.476	100	0.41
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.476	100	0.41
comE/comE2	Streptococcus equinus JB1	41.393	97.992	0.406
comE	Streptococcus mitis NCTC 12261	38.8	100	0.39
comE	Streptococcus mitis SK321	38.8	100	0.39
comE	Streptococcus pneumoniae TIGR4	38.4	100	0.386
comE	Streptococcus pneumoniae Rx1	38.4	100	0.386
comE	Streptococcus pneumoniae D39	38.4	100	0.386
comE	Streptococcus pneumoniae R6	38.4	100	0.386
comE	Streptococcus infantis strain Atu-4	38.306	99.598	0.382