Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   FGL00_RS00735 Genome accession   NZ_LR594034
Coordinates   121579..121905 (+) Length   108 a.a.
NCBI ID   WP_003055259.1    Uniprot ID   A0A9X8T184
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 116579..126905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS00720 (NCTC8546_00148) - 119223..119588 (+) 366 WP_003055257.1 DUF1033 family protein -
  FGL00_RS00725 (NCTC8546_00149) comGA/cglA 119669..120610 (+) 942 WP_138098129.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL00_RS00730 (NCTC8546_00150) comYB 120546..121577 (+) 1032 WP_138098784.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL00_RS00735 (NCTC8546_00151) comYC 121579..121905 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL00_RS00740 (NCTC8546_00152) comGD 121880..122308 (+) 429 WP_014611932.1 competence type IV pilus minor pilin ComGD -
  FGL00_RS00745 (NCTC8546_00153) comGE 122316..122561 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE -
  FGL00_RS00750 (NCTC8546_00154) comGF 122542..122982 (+) 441 WP_138098131.1 competence type IV pilus minor pilin ComGF -
  FGL00_RS00755 (NCTC8546_00155) comGG 123005..123334 (+) 330 WP_003058539.1 competence type IV pilus minor pilin ComGG -
  FGL00_RS00760 (NCTC8546_00156) comYH 123397..124350 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  FGL00_RS00765 (NCTC8546_00157) - 124409..125605 (+) 1197 WP_138098133.1 acetate kinase -
  FGL00_RS00770 (NCTC8546_00158) - 125911..126117 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  FGL00_RS00775 (NCTC8546_00159) - 126220..126900 (+) 681 WP_003060329.1 type II CAAX endopeptidase family protein -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12384.38 Da        Isoelectric Point: 9.6412

>NTDB_id=1127218 FGL00_RS00735 WP_003055259.1 121579..121905(+) (comYC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MKNQWKPLRQYQLQAFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKT
DGSITDKQVKAYTDYYGKHRDETQKLQP

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1127218 FGL00_RS00735 WP_003055259.1 121579..121905(+) (comYC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGAAAAACCAATGGAAACCATTACGGCAATACCAACTACAAGCTTTCACACTTCTAGAAATGTTACTGGTAATTTTAGT
CATCAGTGTCTTAATGCTCTTATTTGTACCTAATTTAAGCAAACAAAAAGATAGGGTTACCGAAACAGGAAATGCTGCTG
TTGTCAAATTAGTGGAGAATCAAGCAGAGTTGTACGAATTATCGCAAGGATCAAAACCAAGTTTAAGTCAATTAAAGACT
GATGGCAGTATTACAGATAAGCAGGTAAAAGCTTACACAGACTATTATGGAAAACACAGAGATGAGACTCAAAAACTGCA
ACCTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

60.194

95.37

0.574

  comGC/cglC Streptococcus mitis SK321

53.774

98.148

0.528

  comGC Lactococcus lactis subsp. cremoris KW2

54.369

95.37

0.519

  comGC/cglC Streptococcus mitis NCTC 12261

55.556

91.667

0.509

  comGC/cglC Streptococcus pneumoniae Rx1

51.887

98.148

0.509

  comGC/cglC Streptococcus pneumoniae D39

51.887

98.148

0.509

  comGC/cglC Streptococcus pneumoniae R6

51.887

98.148

0.509

  comGC/cglC Streptococcus pneumoniae TIGR4

51.402

99.074

0.509

  comYC Streptococcus mutans UA140

53.465

93.519

0.5

  comYC Streptococcus mutans UA159

53.465

93.519

0.5

  comYC Streptococcus suis isolate S10

50.562

82.407

0.417


Multiple sequence alignment