Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGK81_RS09120 Genome accession   NZ_LR590466
Coordinates   1768000..1768938 (-) Length   312 a.a.
NCBI ID   WP_011888534.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8193     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1763000..1773938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK81_RS09080 (NCTC8193_01806) - 1763015..1764211 (-) 1197 WP_011888536.1 acetate kinase -
  FGK81_RS09085 (NCTC8193_01807) comYH 1764270..1765223 (-) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  FGK81_RS09090 (NCTC8193_01808) comGG 1765321..1765647 (-) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  FGK81_RS09095 (NCTC8193_01809) comYF 1765631..1766065 (-) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGK81_RS09100 (NCTC8193_01810) comGE 1766058..1766342 (-) 285 WP_041174183.1 competence type IV pilus minor pilin ComGE -
  FGK81_RS09105 (NCTC8193_01811) comGD 1766299..1766727 (-) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  FGK81_RS09110 (NCTC8193_01812) comYC 1766702..1767028 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  FGK81_RS09115 (NCTC8193_01813) comYB 1767030..1768064 (-) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGK81_RS09120 (NCTC8193_01814) comYA 1768000..1768938 (-) 939 WP_011888534.1 competence type IV pilus ATPase ComGA Machinery gene
  FGK81_RS09125 (NCTC8193_01815) - 1769031..1769396 (-) 366 WP_002986560.1 DUF1033 family protein -
  FGK81_RS09130 (NCTC8193_01816) rpoC 1769548..1773189 (-) 3642 WP_011888533.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35101.38 Da        Isoelectric Point: 8.5799

>NTDB_id=1126811 FGK81_RS09120 WP_011888534.1 1768000..1768938(-) (comYA) [Streptococcus pyogenes strain NCTC8193]
MVQVLAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGITKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1126811 FGK81_RS09120 WP_011888534.1 1768000..1768938(-) (comYA) [Streptococcus pyogenes strain NCTC8193]
ATGGTACAAGTATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTATAACGAAAGCAGAACTATCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.521

99.679

0.583
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

40

92.949

0.372

Multiple sequence alignment