Detailed information NTG1126808

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: FGK81_RS09095
• Genome accession: NZ_LR590466
• Coordinates: 1765631..1766065 (-)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8193
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1760631..1771065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK81_RS09070 (NCTC8193_01805)	proC	1761667..1762437 (+)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-
FGK81_RS09075	-	1762520..1762828 (-)	309	WP_011017251.1	hypothetical protein	-
FGK81_RS09080 (NCTC8193_01806)	-	1763015..1764211 (-)	1197	WP_011888536.1	acetate kinase	-
FGK81_RS09085 (NCTC8193_01807)	comYH	1764270..1765223 (-)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
FGK81_RS09090 (NCTC8193_01808)	comGG	1765321..1765647 (-)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
FGK81_RS09095 (NCTC8193_01809)	comYF	1765631..1766065 (-)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGK81_RS09100 (NCTC8193_01810)	comGE	1766058..1766342 (-)	285	WP_041174183.1	competence type IV pilus minor pilin ComGE	-
FGK81_RS09105 (NCTC8193_01811)	comGD	1766299..1766727 (-)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
FGK81_RS09110 (NCTC8193_01812)	comYC	1766702..1767028 (-)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
FGK81_RS09115 (NCTC8193_01813)	comYB	1767030..1768064 (-)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGK81_RS09120 (NCTC8193_01814)	comYA	1768000..1768938 (-)	939	WP_011888534.1	competence type IV pilus ATPase ComGA	Machinery gene
FGK81_RS09125 (NCTC8193_01815)	-	1769031..1769396 (-)	366	WP_002986560.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=1126808 FGK81_RS09095 WP_002986542.1 1765631..1766065(-) (comYF) [Streptococcus pyogenes strain NCTC8193]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1126808 FGK81_RS09095 WP_002986542.1 1765631..1766065(-) (comYF) [Streptococcus pyogenes strain NCTC8193]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396