Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL107_RS07190 Genome accession   NZ_LR134314
Coordinates   1425238..1426176 (-) Length   312 a.a.
NCBI ID   WP_002986557.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8302     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1420238..1431176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL107_RS07150 (NCTC8302_01415) - 1420253..1421449 (-) 1197 WP_002986533.1 acetate kinase -
  EL107_RS07155 (NCTC8302_01416) comYH 1421508..1422461 (-) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  EL107_RS07160 (NCTC8302_01417) comGG 1422559..1422885 (-) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EL107_RS07165 (NCTC8302_01418) comYF 1422869..1423303 (-) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL107_RS07170 (NCTC8302_01419) comGE 1423296..1423580 (-) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE -
  EL107_RS07175 (NCTC8302_01420) comGD 1423537..1423965 (-) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD -
  EL107_RS07180 (NCTC8302_01421) comYC 1423940..1424266 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EL107_RS07185 (NCTC8302_01422) comYB 1424268..1425302 (-) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL107_RS07190 (NCTC8302_01423) comYA 1425238..1426176 (-) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  EL107_RS07195 (NCTC8302_01424) - 1426269..1426634 (-) 366 WP_002986560.1 DUF1033 family protein -
  EL107_RS07200 (NCTC8302_01425) rpoC 1426786..1430427 (-) 3642 WP_011184087.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35087.35 Da        Isoelectric Point: 8.5799

>NTDB_id=1121153 EL107_RS07190 WP_002986557.1 1425238..1426176(-) (comYA) [Streptococcus pyogenes strain NCTC8302]
MVQVLAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1121153 EL107_RS07190 WP_002986557.1 1425238..1426176(-) (comYA) [Streptococcus pyogenes strain NCTC8302]
ATGGTACAAGTATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.679

0.606
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.645

99.359

0.603
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment