Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EL107_RS07155 Genome accession   NZ_LR134314
Coordinates   1421508..1422461 (-) Length   317 a.a.
NCBI ID   WP_021340467.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8302     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1416508..1427461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL107_RS07120 (NCTC8302_01411) - 1416727..1417044 (-) 318 WP_002986515.1 thioredoxin family protein -
  EL107_RS07125 (NCTC8302_01412) - 1417041..1417325 (-) 285 WP_011888537.1 DUF4651 domain-containing protein -
  EL107_RS07135 (NCTC8302_01413) pepA 1417790..1418857 (+) 1068 WP_011184093.1 glutamyl aminopeptidase -
  EL107_RS07140 (NCTC8302_01414) proC 1418905..1419675 (+) 771 WP_011184092.1 pyrroline-5-carboxylate reductase -
  EL107_RS07145 - 1419758..1420066 (-) 309 WP_011017251.1 hypothetical protein -
  EL107_RS07150 (NCTC8302_01415) - 1420253..1421449 (-) 1197 WP_002986533.1 acetate kinase -
  EL107_RS07155 (NCTC8302_01416) comYH 1421508..1422461 (-) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  EL107_RS07160 (NCTC8302_01417) comGG 1422559..1422885 (-) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EL107_RS07165 (NCTC8302_01418) comYF 1422869..1423303 (-) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL107_RS07170 (NCTC8302_01419) comGE 1423296..1423580 (-) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE -
  EL107_RS07175 (NCTC8302_01420) comGD 1423537..1423965 (-) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD -
  EL107_RS07180 (NCTC8302_01421) comYC 1423940..1424266 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EL107_RS07185 (NCTC8302_01422) comYB 1424268..1425302 (-) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL107_RS07190 (NCTC8302_01423) comYA 1425238..1426176 (-) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  EL107_RS07195 (NCTC8302_01424) - 1426269..1426634 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35971.05 Da        Isoelectric Point: 4.7205

>NTDB_id=1121149 EL107_RS07155 WP_021340467.1 1421508..1422461(-) (comYH) [Streptococcus pyogenes strain NCTC8302]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFVQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1121149 EL107_RS07155 WP_021340467.1 1421508..1422461(-) (comYH) [Streptococcus pyogenes strain NCTC8302]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAATTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTGTTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

66.456

99.685

0.662
  comYH Streptococcus mutans UA140

66.139

99.685

0.659

Multiple sequence alignment