Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL084_RS07155 Genome accession   NZ_LR134292
Coordinates   1429794..1430735 (+) Length   313 a.a.
NCBI ID   WP_126439866.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1424794..1435735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS07145 (NCTC10389_01514) rpoC 1425552..1429190 (+) 3639 WP_126439864.1 DNA-directed RNA polymerase subunit beta' -
  EL084_RS07150 (NCTC10389_01515) - 1429357..1429725 (+) 369 WP_126439865.1 DUF1033 family protein -
  EL084_RS07155 (NCTC10389_01516) comYA 1429794..1430735 (+) 942 WP_126439866.1 competence type IV pilus ATPase ComGA Machinery gene
  EL084_RS07160 comGB 1430659..1431701 (+) 1043 Protein_1373 competence type IV pilus assembly protein ComGB -
  EL084_RS07165 (NCTC10389_01519) comYC 1431701..1432003 (+) 303 WP_003067906.1 competence type IV pilus major pilin ComGC Machinery gene
  EL084_RS07170 (NCTC10389_01520) comGD 1431978..1432418 (+) 441 WP_003067905.1 competence type IV pilus minor pilin ComGD -
  EL084_RS07175 (NCTC10389_01521) comGE 1432372..1432665 (+) 294 WP_003067904.1 competence type IV pilus minor pilin ComGE -
  EL084_RS07180 (NCTC10389_01522) comYF 1432649..1433086 (+) 438 WP_003067903.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL084_RS07185 (NCTC10389_01523) comGG 1433097..1433408 (+) 312 WP_268921724.1 competence type IV pilus minor pilin ComGG -
  EL084_RS07190 (NCTC10389_01524) comYH 1433462..1434418 (+) 957 WP_115254812.1 class I SAM-dependent methyltransferase Machinery gene
  EL084_RS07195 (NCTC10389_01525) - 1434472..1435671 (+) 1200 WP_126439867.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35719.88 Da        Isoelectric Point: 6.3684

>NTDB_id=1120454 EL084_RS07155 WP_126439866.1 1429794..1430735(+) (comYA) [Streptococcus equinus strain NCTC10389]
MIQEKAKQLIRDAVGKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIVYQRLIGGGGVVDFAKRDFEQYPPRRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1120454 EL084_RS07155 WP_126439866.1 1429794..1430735(+) (comYA) [Streptococcus equinus strain NCTC10389]
ATGATTCAGGAAAAAGCAAAGCAGCTTATTAGAGATGCAGTTGGAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAACGCCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGTCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTATCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAATATTTTAGAGGCTATTGACAGCAGGGGAC
TTTACCTTTTTTCCGGGCCGGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTAGTTCGTGAAAAATTTCCTGGAAAA
CAGGTGATTACGATTGAAGACCCTGTTGAGATAAAACAAGACAATATGTTGCAATTGCAGTTAAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACCATTCATGCGAAAAGTATTCCAGGTGTT
TATGCTAGGTTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGTGCTATTGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAAGAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.387

99.042

0.677
  comYA Streptococcus gordonii str. Challis substr. CH1

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

63.782

99.681

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

54.633

100

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment