Detailed information NTG1120171

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: EL100_RS03770
• Genome accession: NZ_LR134285
• Coordinates: 715361..716113 (+)
• Length: 250 a.a.
• NCBI ID: WP_126405015.1
• Uniprot ID: -
• Organism: Streptococcus australis strain NCTC3168
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 710361..721113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL100_RS03740 (NCTC3168_00773)	spo0J	710851..711612 (-)	762	WP_126405019.1	ParB/RepB/Spo0J family partition protein	Regulator
EL100_RS03745 (NCTC3168_00774)	htrA	711678..712856 (-)	1179	WP_126405018.1	S1C family serine protease	Regulator
EL100_RS03750 (NCTC3168_00775)	rlmH	713059..713538 (+)	480	WP_126405017.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL100_RS03760 (NCTC3168_00777)	-	713898..714041 (+)	144	WP_126405016.1	bacteriocin	-
EL100_RS09760 (NCTC3168_00778)	-	714041..715360 (+)	1320	WP_232011417.1	GHKL domain-containing protein	-
EL100_RS03770 (NCTC3168_00779)	comE/comE2	715361..716113 (+)	753	WP_126405015.1	response regulator transcription factor	Regulator
EL100_RS03785 (NCTC3168_00782)	-	716396..718984 (-)	2589	WP_126405014.1	YfhO family protein	-
EL100_RS03790 (NCTC3168_00783)	-	719047..720669 (-)	1623	WP_006595336.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29426.18 Da
• Isoelectric Point: 8.4082

>NTDB_id=1120171 EL100_RS03770 WP_126405015.1 715361..716113(+) (comE/comE2) [Streptococcus australis strain NCTC3168]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKITELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIVDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVSFDRRKRLLMLEEETTCPVSRTQVKRVE
ELLNKIQKKA

Nucleotide

• Length: 753 bp

>NTDB_id=1120171 EL100_RS03770 WP_126405015.1 715361..716113(+) (comE/comE2) [Streptococcus australis strain NCTC3168]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTGAAAGCTATCGCTGAGGAGGA
AGGACTACGATTAAATATTGTTTCCACCAGTAAAATAACTGAATTAAAGGAATACCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTTGATATTGATATCAAAGGGGATGAAAAAGCTGGCATCAAGGCAGCTCAAATGATTCGCGAGGTCAATCCT
TTTGCCATCATTGCCTTTATTACGACGAAATCGGAATTTGCTACCATTACTTATCGTTACAAGGTATCAGCTCTTGAATT
TATTGAAAAAACCTTGAATGAAAACTTGTTTAAAGAAAAAATTCGAGAATGCATTCTTTACTTGAAGAAGAATGTGATTG
AAAATAAAAATATCGTTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTGCCATATCGAGATATATTGTAC
ATTGAAACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTGGACAATCATTTCTTCAGTCCTAATCAGTCTTATCTAGTGAATCAAAGAATGATTGTCAGTT
TTGATCGTCGCAAGAGACTCTTGATGTTAGAAGAGGAGACAACTTGCCCTGTTTCTCGTACACAGGTGAAAAGGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-243)

• Response regulator receiver domain (Response_reg) (18-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	50.4	100	0.504
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	50.4	100	0.504
comE	Streptococcus infantis strain Atu-4	49.2	100	0.492
comE	Streptococcus mitis SK321	48	100	0.48
comE	Streptococcus mitis NCTC 12261	48	100	0.48
comE	Streptococcus pneumoniae Rx1	47.2	100	0.472
comE	Streptococcus pneumoniae D39	47.2	100	0.472
comE	Streptococcus pneumoniae R6	47.2	100	0.472
comE	Streptococcus pneumoniae TIGR4	47.2	100	0.472
comE/comE1	Streptococcus equinus JB1	37.805	98.4	0.372