Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EL100_RS03745 Genome accession   NZ_LR134285
Coordinates   711678..712856 (-) Length   392 a.a.
NCBI ID   WP_126405018.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 706678..717856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS03720 (NCTC3168_00769) - 707401..707643 (+) 243 WP_232011416.1 DUF1307 domain-containing protein -
  EL100_RS03725 (NCTC3168_00770) - 707679..707870 (-) 192 WP_126403553.1 DUF951 domain-containing protein -
  EL100_RS03730 (NCTC3168_00771) dnaN 707934..709070 (-) 1137 WP_126403552.1 DNA polymerase III subunit beta -
  EL100_RS03735 (NCTC3168_00772) dnaA 709231..710601 (-) 1371 WP_126403551.1 chromosomal replication initiator protein DnaA -
  EL100_RS03740 (NCTC3168_00773) spo0J 710851..711612 (-) 762 WP_126405019.1 ParB/RepB/Spo0J family partition protein Regulator
  EL100_RS03745 (NCTC3168_00774) htrA 711678..712856 (-) 1179 WP_126405018.1 S1C family serine protease Regulator
  EL100_RS03750 (NCTC3168_00775) rlmH 713059..713538 (+) 480 WP_126405017.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EL100_RS03760 (NCTC3168_00777) - 713898..714041 (+) 144 WP_126405016.1 bacteriocin -
  EL100_RS09760 (NCTC3168_00778) - 714041..715360 (+) 1320 WP_232011417.1 GHKL domain-containing protein -
  EL100_RS03770 (NCTC3168_00779) comE/comE2 715361..716113 (+) 753 WP_126405015.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 392 a.a.        Molecular weight: 41336.69 Da        Isoelectric Point: 5.1173

>NTDB_id=1120170 EL100_RS03745 WP_126405018.1 711678..712856(-) (htrA) [Streptococcus australis strain NCTC3168]
MKQPSNFLKKALQLLLVLVIGFTGGILGTLTSFQFTKGNSTNSSQEIKSTIVNRAYKNTTSTSEAVDKVKNAVVSVITYA
ETSEKGFINGETDTDPEVASEGSGVIYKKDGKDAYVVTNAHVLMGATEADILFADGNKVSGEVVGSDTFSDIAVVKISSD
NVTTVAEFGDSSKLTVGETAIAIGSPLGTKFANSVTQGIVSSLGRTVKLKSEDGQNVSTKALQTDAAINPGNSGGPLINI
QGQVIGITSSKISSNGQTAVEGMGFAIPVNDVQNIIEHLEKDGKVIRPALGITMMDLASLSSSDLSQLDIPSKLKGGVLV
RSVENDMPASKYLRRLDIITKIDDTTIESTADLQSALYSHQIGDKIKVIFYRDGKQKTATIELTKSTENLGN

Nucleotide


Download         Length: 1179 bp        

>NTDB_id=1120170 EL100_RS03745 WP_126405018.1 711678..712856(-) (htrA) [Streptococcus australis strain NCTC3168]
ATGAAACAACCATCAAATTTTCTAAAAAAAGCTTTGCAACTTTTGCTTGTTCTTGTCATTGGGTTTACTGGAGGAATCTT
AGGAACCTTAACCTCTTTCCAGTTTACCAAAGGGAATTCTACAAATTCTAGCCAAGAAATAAAATCTACCATAGTCAATC
GTGCTTATAAGAATACAACATCAACTAGTGAAGCCGTTGATAAGGTTAAAAATGCTGTTGTTTCTGTTATTACCTACGCT
GAAACCTCTGAAAAAGGCTTCATCAATGGAGAAACAGATACTGATCCAGAAGTAGCTAGTGAAGGTTCAGGTGTTATCTA
TAAAAAAGATGGGAAAGACGCTTATGTAGTAACCAATGCTCACGTGTTAATGGGAGCAACAGAAGCAGATATTCTCTTTG
CAGACGGAAATAAAGTTTCCGGAGAAGTTGTTGGTTCAGATACCTTCTCAGATATTGCGGTTGTCAAAATCAGTTCAGAC
AATGTTACGACCGTGGCTGAATTTGGAGATTCATCTAAGTTGACTGTCGGAGAGACCGCAATCGCTATTGGTAGTCCTTT
AGGGACAAAATTTGCCAATTCCGTTACCCAAGGGATTGTCTCTAGTCTCGGACGTACTGTGAAGCTCAAATCAGAAGACG
GCCAAAATGTGTCTACAAAAGCGTTGCAAACGGACGCTGCCATCAACCCAGGAAATTCTGGTGGTCCCCTTATCAATATT
CAGGGACAAGTCATCGGAATTACCTCAAGTAAAATCTCTTCAAATGGGCAAACTGCGGTTGAAGGAATGGGATTTGCTAT
TCCTGTAAATGATGTGCAAAATATTATTGAACATTTAGAAAAAGATGGTAAAGTCATTCGTCCAGCTCTTGGAATTACCA
TGATGGACCTGGCTAGCCTATCCTCTTCTGATCTTAGCCAATTAGACATTCCAAGCAAACTCAAAGGTGGGGTTCTTGTC
CGCTCAGTTGAAAATGATATGCCGGCATCCAAGTATTTACGTCGATTAGATATCATTACAAAAATCGATGATACAACCAT
TGAATCAACTGCGGATTTACAATCTGCCCTCTATTCTCATCAAATTGGTGATAAAATCAAAGTTATTTTCTATAGAGATG
GTAAGCAAAAAACAGCGACCATTGAGCTGACAAAATCTACAGAAAATCTTGGAAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(233-388)

PDZ domain (PDZ_2)

(288-383)

Trypsin-like peptidase domain (Trypsin_2)

(102-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

63.52

100

0.635
  htrA Streptococcus pneumoniae Rx1

63.265

100

0.633
  htrA Streptococcus pneumoniae D39

63.265

100

0.633
  htrA Streptococcus pneumoniae R6

63.265

100

0.633
  htrA Streptococcus pneumoniae TIGR4

63.265

100

0.633
  htrA Streptococcus gordonii str. Challis substr. CH1

62.183

100

0.625
  htrA Streptococcus mutans UA159

52.273

100

0.528

Multiple sequence alignment