Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ELZ51_RS00850 Genome accession   NZ_LR134094
Coordinates   130244..131185 (+) Length   313 a.a.
NCBI ID   WP_126425651.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125244..136185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS00840 (NCTC4669_00178) rpoC 125954..129595 (+) 3642 WP_126425647.1 DNA-directed RNA polymerase subunit beta' -
  ELZ51_RS00845 (NCTC4669_00179) - 129798..130163 (+) 366 WP_126425649.1 DUF1033 family protein -
  ELZ51_RS00850 (NCTC4669_00180) comYA 130244..131185 (+) 942 WP_126425651.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ51_RS00855 (NCTC4669_00181) comYB 131121..132152 (+) 1032 WP_126427580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ51_RS00860 (NCTC4669_00182) comYC 132154..132480 (+) 327 WP_115246891.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ51_RS00865 (NCTC4669_00183) comGD 132455..132883 (+) 429 WP_115252504.1 competence type IV pilus minor pilin ComGD -
  ELZ51_RS00870 (NCTC4669_00184) comGE 132840..133136 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  ELZ51_RS00875 (NCTC4669_00185) comGF 133117..133557 (+) 441 WP_003049266.1 competence type IV pilus minor pilin ComGF -
  ELZ51_RS00880 (NCTC4669_00186) comGG 133580..133909 (+) 330 WP_226316716.1 competence type IV pilus minor pilin ComGG -
  ELZ51_RS00885 (NCTC4669_00187) comYH 133972..134925 (+) 954 WP_126425653.1 class I SAM-dependent methyltransferase Machinery gene
  ELZ51_RS00890 (NCTC4669_00188) - 134984..136180 (+) 1197 WP_003049273.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35236.37 Da        Isoelectric Point: 7.9044

>NTDB_id=1118253 ELZ51_RS00850 WP_126425651.1 130244..131185(+) (comYA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MVQALARSILKEAEQIQAQDIYILPKENQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHRQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGALVFSTVHAKSISGV
YARLLELGVTRAELDNCLAFVAYQRLLNGGALIDSTQTEFEHYSPNQWNQQIDDLLAAGHLSPKQARIEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1118253 ELZ51_RS00850 WP_126425651.1 130244..131185(+) (comYA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AAATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTGCGCCTATCTAGTGTTGGAAATTACCGTGGACAAGAGAGTTTAGTGATTCGGTT
ACTGCATCATCGACAAAGAAGTTTACACTACTGGTTTGACGGACTGAAAACAGTCGCACGTCAGATTGGAGGCCGAGGGC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGGAAAACAACTTTGATGCACCAATTGATTGCTGATTATTATCAGGGAGCA
CAGGTCATTAGCATAGAGGATCCGGTGGAAATCAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGCCTTAGTATTTTCAACAGTGCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTTGTTGCTTACCAACGATTGCT
TAATGGAGGGGCATTAATTGACTCAACTCAGACAGAATTTGAACACTACTCACCAAACCAATGGAATCAACAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGAAGCAAGCAAGGATCGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.379

99.361

0.62
  comYA Streptococcus mutans UA159

62.379

99.361

0.62
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

99.042

0.61
  comYA Streptococcus gordonii str. Challis substr. CH1

61.093

99.361

0.607
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.129

99.361

0.597
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511

Multiple sequence alignment