Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ELZ51_RS00855 Genome accession   NZ_LR134094
Coordinates   131121..132152 (+) Length   343 a.a.
NCBI ID   WP_126427580.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 126121..137152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS00845 (NCTC4669_00179) - 129798..130163 (+) 366 WP_126425649.1 DUF1033 family protein -
  ELZ51_RS00850 (NCTC4669_00180) comYA 130244..131185 (+) 942 WP_126425651.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ51_RS00855 (NCTC4669_00181) comYB 131121..132152 (+) 1032 WP_126427580.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ51_RS00860 (NCTC4669_00182) comYC 132154..132480 (+) 327 WP_115246891.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ51_RS00865 (NCTC4669_00183) comGD 132455..132883 (+) 429 WP_115252504.1 competence type IV pilus minor pilin ComGD -
  ELZ51_RS00870 (NCTC4669_00184) comGE 132840..133136 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  ELZ51_RS00875 (NCTC4669_00185) comGF 133117..133557 (+) 441 WP_003049266.1 competence type IV pilus minor pilin ComGF -
  ELZ51_RS00880 (NCTC4669_00186) comGG 133580..133909 (+) 330 WP_226316716.1 competence type IV pilus minor pilin ComGG -
  ELZ51_RS00885 (NCTC4669_00187) comYH 133972..134925 (+) 954 WP_126425653.1 class I SAM-dependent methyltransferase Machinery gene
  ELZ51_RS00890 (NCTC4669_00188) - 134984..136180 (+) 1197 WP_003049273.1 acetate kinase -
  ELZ51_RS00895 (NCTC4669_00189) - 136490..136696 (+) 207 WP_003049274.1 helix-turn-helix transcriptional regulator -
  ELZ51_RS00900 (NCTC4669_00190) - 136744..137058 (+) 315 Protein_131 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38963.27 Da        Isoelectric Point: 9.2064

>NTDB_id=1118254 ELZ51_RS00855 WP_126427580.1 131121..132152(+) (comYB) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MTFLQRDISVRSKQGSKKLSSKERYKLIQLLANLLLTGFNLTEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMMLGLRHYVMPHLEAQNQLTIFLTH
FPAIFFAIILFIGVLSGGIWLHWRSQSHLKLFTHLSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMTMEKSL
FMQELAEDIRVSLLSGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1118254 ELZ51_RS00855 WP_126427580.1 131121..132152(+) (comYB) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGAAGCAAGCAAGGATCGAAAAAATTATCCAGTAAGGAACGATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACCTGACGGAGATAATAGCTTTCTTAACAAAAAGTCATCTGA
TTCCCGAGCCCTATGTTCTTCGTATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGGAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTTCTGGTATTTCTTT
TTGTAATGATGTTAGGGTTAAGGCATTATGTTATGCCTCACTTAGAAGCTCAAAATCAGCTTACTATTTTTCTCACTCAT
TTTCCAGCTATTTTCTTTGCTATTATCCTTTTTATCGGTGTACTGTCAGGAGGAATTTGGCTGCATTGGCGATCGCAAAG
TCACCTCAAGCTTTTTACTCACCTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGACCATGGAGAAATCTTTA
TTTATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTACTGTCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTTAGCCAGCTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.392

98.834

0.528
  comYB Streptococcus mutans UA159

53.392

98.834

0.528
  comYB Streptococcus gordonii str. Challis substr. CH1

48.083

98.834

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

45.238

97.959

0.443
  comGB/cglB Streptococcus mitis SK321

45.045

97.085

0.437
  comGB/cglB Streptococcus pneumoniae Rx1

43.544

97.085

0.423
  comGB/cglB Streptococcus pneumoniae D39

43.544

97.085

0.423
  comGB/cglB Streptococcus pneumoniae R6

43.544

97.085

0.423
  comGB/cglB Streptococcus pneumoniae TIGR4

43.544

97.085

0.423
  comGB Lactococcus lactis subsp. cremoris KW2

42.604

98.542

0.42

Multiple sequence alignment