Detailed information NTG1117827

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ELZ47_RS08190
• Genome accession: NZ_LR134002
• Coordinates: 1653638..1654318 (-)
• Length: 226 a.a.
• NCBI ID: WP_126435770.1
• Uniprot ID: A0AAJ5TAF6
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1648638..1659318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS08175 (NCTC10904_01605)	holA	1648853..1649899 (-)	1047	WP_126435767.1	DNA polymerase III subunit delta	-
ELZ47_RS08180 (NCTC10904_01606)	-	1650150..1651289 (-)	1140	WP_126435768.1	DUF805 domain-containing protein	-
ELZ47_RS08185 (NCTC10904_01607)	comEC/celB	1651414..1653654 (-)	2241	WP_126435769.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ELZ47_RS08190 (NCTC10904_01608)	comEA	1653638..1654318 (-)	681	WP_126435770.1	helix-hairpin-helix domain-containing protein	Machinery gene
ELZ47_RS08195 (NCTC10904_01609)	-	1654467..1655015 (-)	549	WP_164549596.1	HXXEE domain-containing protein	-
ELZ47_RS08200 (NCTC10904_01610)	-	1655088..1655828 (-)	741	WP_002900842.1	lysophospholipid acyltransferase family protein	-
ELZ47_RS08205 (NCTC10904_01611)	-	1655986..1658325 (+)	2340	WP_126435772.1	cation-translocating P-type ATPase	-
ELZ47_RS08210 (NCTC10904_01612)	-	1658455..1659201 (+)	747	WP_126435773.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 23984.83 Da
• Isoelectric Point: 4.7351

>NTDB_id=1117827 ELZ47_RS08190 WP_126435770.1 1653638..1654318(-) (comEA) [Streptococcus sanguinis strain NCTC 10904]
MLEEIIEKLKEYKLFVGLAVVGAVLGCFFLIKGNHQPQNQVAVLSQEITSSSSSADEESEKIVSKVKADEEESEQVTVDI
KGAVKNPGVYELRAGARVHEAIQKAGGLTADAEAKSINQAQKLTDEAVIYVAKIGEEGADVTQTGQHQAGASDSAGASGG
KSDKVNLNTATEAELQTISGIGQKRASDIIAYRESSGRFKSVDDLKKVSGIGDKTLEKLKEYVTVD

Nucleotide

• Length: 681 bp

>NTDB_id=1117827 ELZ47_RS08190 WP_126435770.1 1653638..1654318(-) (comEA) [Streptococcus sanguinis strain NCTC 10904]
ATGCTTGAAGAAATCATTGAAAAGCTGAAAGAATACAAGCTCTTTGTCGGTCTGGCAGTGGTTGGCGCTGTTCTAGGTTG
TTTTTTCCTTATCAAAGGAAATCATCAACCGCAAAATCAGGTCGCTGTCTTGAGTCAAGAAATAACTTCCTCATCCAGCT
CAGCTGATGAAGAAAGCGAAAAGATTGTCTCTAAGGTCAAGGCGGACGAAGAAGAGAGTGAGCAAGTCACTGTGGATATA
AAGGGAGCAGTCAAGAATCCTGGTGTCTATGAGCTAAGAGCAGGAGCGAGAGTCCATGAAGCCATCCAAAAAGCTGGCGG
ATTGACAGCAGACGCCGAGGCTAAGTCCATCAATCAGGCACAAAAATTAACGGATGAAGCAGTAATCTATGTGGCAAAGA
TTGGTGAAGAAGGAGCCGATGTCACACAGACTGGTCAGCATCAAGCAGGAGCTTCTGATTCTGCCGGTGCCAGTGGCGGA
AAGTCAGACAAGGTCAATCTAAATACGGCGACAGAGGCTGAACTGCAGACTATTTCAGGCATCGGACAGAAGCGGGCTTC
TGACATCATCGCCTACCGAGAAAGCAGTGGCCGCTTTAAGTCAGTAGATGATCTGAAAAAGGTGTCAGGTATTGGAGATA
AGACCTTAGAAAAGCTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (78-131)

• Helix-hairpin-helix motif (HHH_3) (162-224)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	50	100	0.513
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	50.442	100	0.504
comEA/celA/cilE	Streptococcus pneumoniae Rx1	48.707	100	0.5
comEA/celA/cilE	Streptococcus pneumoniae D39	48.707	100	0.5
comEA/celA/cilE	Streptococcus pneumoniae R6	48.707	100	0.5
comEA/celA/cilE	Streptococcus mitis SK321	48.673	100	0.487
comEA/celA/cilE	Streptococcus mitis NCTC 12261	48.889	99.558	0.487
comEA	Bacillus subtilis subsp. subtilis str. 168	42.986	97.788	0.42
comEA	Lactococcus lactis subsp. cremoris KW2	39.648	100	0.398
comEA	Latilactobacillus sakei subsp. sakei 23K	34.413	100	0.376