Detailed information NTG1117826

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ELZ47_RS08185
• Genome accession: NZ_LR134002
• Coordinates: 1651414..1653654 (-)
• Length: 746 a.a.
• NCBI ID: WP_126435769.1
• Uniprot ID: A0AAJ5TAU9
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1646414..1658654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS08160 (NCTC10904_01602)	-	1646619..1646759 (-)	141	WP_002897970.1	hypothetical protein	-
ELZ47_RS08165 (NCTC10904_01603)	-	1646970..1648049 (-)	1080	WP_331852790.1	serine hydrolase	-
ELZ47_RS08170 (NCTC10904_01604)	sodA	1648185..1648790 (-)	606	WP_002906995.1	superoxide dismutase SodA	-
ELZ47_RS08175 (NCTC10904_01605)	holA	1648853..1649899 (-)	1047	WP_126435767.1	DNA polymerase III subunit delta	-
ELZ47_RS08180 (NCTC10904_01606)	-	1650150..1651289 (-)	1140	WP_126435768.1	DUF805 domain-containing protein	-
ELZ47_RS08185 (NCTC10904_01607)	comEC/celB	1651414..1653654 (-)	2241	WP_126435769.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ELZ47_RS08190 (NCTC10904_01608)	comEA	1653638..1654318 (-)	681	WP_126435770.1	helix-hairpin-helix domain-containing protein	Machinery gene
ELZ47_RS08195 (NCTC10904_01609)	-	1654467..1655015 (-)	549	WP_164549596.1	HXXEE domain-containing protein	-
ELZ47_RS08200 (NCTC10904_01610)	-	1655088..1655828 (-)	741	WP_002900842.1	lysophospholipid acyltransferase family protein	-
ELZ47_RS08205 (NCTC10904_01611)	-	1655986..1658325 (+)	2340	WP_126435772.1	cation-translocating P-type ATPase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85161.35 Da
• Isoelectric Point: 9.3790

>NTDB_id=1117826 ELZ47_RS08185 WP_126435769.1 1651414..1653654(-) (comEC/celB) [Streptococcus sanguinis strain NCTC 10904]
MSQWIKKLPLAPIYLAFILVWAYFAVYAGSSLAYFGLGVLLLRLFFSYPLKKSLAALAFLSLFVLFFLLRREIAEQAFRQ
EPPSASSVQVLPDTIKVNGDSLSFRGRTDGRLYQVFYKIKSASEKKAFQQLTDLVVLDMEAEFEQAQQQRNFSGFDYQAY
LKSQGIYRTLKINKIQSLRPISSLNPLDWLSVWRRKALVYIRSNFPSPMSHYMTGLLFGDLDTEFAEMSNLYSSLGIIHL
FALSGMQVGFFLDGFRRILLRLGMKRETVNALQLPFSFIYAGLTGFSVSVVRSLVQKLLAQQGLTRLDNFALTLMVLFII
MPNFLLTAGGVLSCAYAFLISMMDFEKLPPIRKLLAESLTISLGILPILIYYFSEFQPWSVILTFLFSLFFDLLMLPGLT
LIFILSPLVKISQANFFFELLEDVIRWVADFTPRPLIFGKPNLWLLFALLLVLALIYDFRRKKSWLLSFSLLTLLLFFLT
RHPLQNEITVVDIGQGDSIFLRDWRGRTVLIDVGGRVEIGKKEAWQERQTSSNAEKTLIPYLKSRGVASLDVLVLTHTDT
DHMGDMLEVAKHFSIKEIYVSKGSLTQLDFVQKLEQIETSVHVVEVGDEIPVFDSVLQVLYPSGTGDGGNDDSIVLYGEF
FQTKFLFTGDLERRGETELLQRFPQLKADVLKAGHHGSKGSSSPEFLEQIQPKLALISAGQNNRYRHPHQETLERFEKFN
TAIYRTDQQGAIRFTGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1117826 ELZ47_RS08185 WP_126435769.1 1651414..1653654(-) (comEC/celB) [Streptococcus sanguinis strain NCTC 10904]
ATGTCACAGTGGATTAAAAAGTTACCCCTCGCACCTATCTATCTGGCTTTCATCCTTGTCTGGGCCTATTTTGCCGTCTA
TGCTGGCAGTTCCTTGGCCTATTTTGGGCTGGGTGTCCTTTTGCTTCGTCTCTTTTTCAGCTATCCTCTCAAAAAAAGTC
TAGCTGCCTTGGCATTTCTGTCCCTTTTTGTCCTCTTTTTCTTACTTCGTCGGGAAATAGCAGAGCAGGCATTTAGGCAG
GAACCTCCTTCAGCTAGCTCGGTTCAGGTCTTGCCAGATACAATCAAAGTCAATGGAGACTCCCTATCCTTTCGAGGGCG
AACGGACGGTCGACTTTATCAGGTCTTCTACAAAATCAAATCAGCCAGTGAAAAGAAAGCTTTTCAGCAACTGACAGATT
TGGTCGTCCTTGATATGGAAGCAGAGTTTGAACAGGCCCAGCAGCAACGAAATTTTTCGGGCTTTGACTATCAGGCTTAT
TTAAAGAGTCAGGGGATTTACCGTACCTTAAAAATCAATAAGATTCAGTCACTAAGACCAATTTCCAGCTTAAATCCACT
GGATTGGCTGTCTGTTTGGCGGAGAAAAGCGCTGGTCTATATTCGAAGTAATTTTCCCAGCCCGATGAGTCATTATATGA
CTGGACTCTTGTTTGGTGACTTGGATACGGAGTTTGCGGAAATGAGCAATCTGTATTCTAGCTTGGGTATCATCCACTTG
TTTGCCTTGTCTGGTATGCAGGTAGGTTTCTTTTTGGATGGTTTTCGCAGGATTCTTCTACGTTTGGGGATGAAGAGGGA
GACAGTAAACGCCTTGCAGCTACCTTTTTCATTTATCTACGCTGGACTGACAGGCTTTTCTGTTTCTGTCGTCAGAAGCT
TAGTTCAGAAGTTGTTGGCCCAGCAAGGACTGACCAGATTAGATAACTTTGCTCTGACACTGATGGTTCTCTTTATCATC
ATGCCCAATTTTCTTCTGACAGCAGGCGGTGTCTTGTCCTGCGCCTATGCCTTTTTGATTTCTATGATGGATTTTGAAAA
GTTACCGCCGATTCGTAAGCTTTTAGCGGAAAGTCTGACTATTTCATTGGGGATTTTGCCTATACTAATCTACTATTTTT
CTGAATTTCAGCCTTGGTCTGTGATTTTAACTTTTCTATTTTCACTATTCTTTGACCTGCTGATGCTACCGGGGTTAACC
CTCATTTTTATTTTGTCACCACTTGTAAAAATTTCTCAGGCCAATTTTTTCTTTGAGTTACTCGAAGATGTGATTCGTTG
GGTAGCTGATTTTACTCCGCGTCCTTTGATTTTTGGGAAGCCCAACCTCTGGTTACTGTTTGCTCTGCTTTTGGTTTTGG
CTTTAATCTATGACTTTCGGAGAAAGAAAAGCTGGCTTTTATCTTTTAGTTTGCTTACTCTTCTCTTATTTTTTCTAACA
AGGCATCCGCTGCAAAACGAGATCACAGTAGTGGATATTGGTCAGGGAGATAGCATTTTTCTCAGGGACTGGCGAGGCAG
GACGGTTTTGATTGATGTAGGAGGACGAGTCGAGATAGGAAAGAAAGAGGCTTGGCAGGAGCGACAGACTTCATCCAATG
CAGAAAAGACCTTAATTCCCTATCTCAAAAGTCGTGGCGTTGCTAGTCTGGATGTATTGGTCCTGACTCATACCGATACC
GATCACATGGGAGATATGCTGGAGGTAGCTAAGCATTTTTCCATCAAGGAAATCTATGTTTCTAAAGGAAGTCTGACTCA
GCTTGATTTTGTTCAAAAACTGGAGCAGATAGAAACTTCTGTCCATGTCGTAGAAGTAGGAGATGAGATTCCGGTGTTTG
ACTCAGTTTTGCAGGTTCTCTATCCCAGCGGGACAGGCGATGGTGGAAATGATGATTCGATTGTACTCTACGGGGAGTTC
TTTCAGACAAAATTTTTGTTTACAGGTGATTTGGAAAGGCGAGGAGAAACTGAACTGCTGCAGCGATTTCCTCAGCTGAA
AGCAGATGTCTTAAAAGCAGGTCACCATGGATCCAAAGGCTCTTCCAGTCCAGAGTTTTTAGAGCAAATTCAGCCGAAAC
TGGCCTTGATATCAGCTGGACAGAATAATCGTTATCGTCATCCCCATCAGGAAACCTTGGAAAGATTTGAGAAGTTTAAT
ACAGCCATCTATCGAACTGACCAGCAGGGGGCCATTCGGTTTACTGGTTGGAATTCCTGGAGGATTGAAACGGTTCGTTG
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Competence protein (Competence) (216-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.564	100	0.576
comEC/celB	Streptococcus mitis NCTC 12261	57.105	100	0.571
comEC/celB	Streptococcus pneumoniae TIGR4	56.627	100	0.567
comEC/celB	Streptococcus pneumoniae Rx1	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae D39	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae R6	56.359	100	0.564
comEC	Lactococcus lactis subsp. cremoris KW2	48.262	100	0.484