Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LFA_RS06985 Genome accession   NZ_LN614827
Coordinates   1722393..1723613 (+) Length   406 a.a.
NCBI ID   WP_045095547.1    Uniprot ID   A0A098G4Q3
Organism   Legionella fallonii LLAP-10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1717393..1728613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LFA_RS06965 (LFA_1559) - 1718283..1718843 (-) 561 WP_045095543.1 hypoxanthine-guanine phosphoribosyltransferase -
  LFA_RS06970 (LFA_1560) - 1718953..1719279 (-) 327 WP_045095544.1 DUF1820 family protein -
  LFA_RS06975 (LFA_1561) - 1719414..1720145 (-) 732 WP_045095545.1 methyltransferase domain-containing protein -
  LFA_RS06980 (LFA_1563) pilB 1720667..1722388 (+) 1722 WP_045095546.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LFA_RS06985 (LFA_1564) pilC 1722393..1723613 (+) 1221 WP_045095547.1 type II secretion system F family protein Machinery gene
  LFA_RS06990 (LFA_1565) pilD 1723654..1724517 (+) 864 WP_045095548.1 A24 family peptidase Machinery gene
  LFA_RS06995 (LFA_1566) - 1724749..1724991 (+) 243 WP_045095549.1 hypothetical protein -
  LFA_RS07000 (LFA_1567) - 1724988..1725431 (+) 444 WP_065814366.1 hypothetical protein -
  LFA_RS07005 (LFA_1568) - 1725463..1725621 (+) 159 WP_157010307.1 hypothetical protein -
  LFA_RS07010 (LFA_1569) - 1725707..1726609 (-) 903 WP_084602133.1 branched-chain amino acid transaminase -
  LFA_RS07015 (LFA_1570) - 1726795..1728477 (-) 1683 WP_045095552.1 hypothetical protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44561.41 Da        Isoelectric Point: 10.0358

>NTDB_id=1113614 LFA_RS06985 WP_045095547.1 1722393..1723613(+) (pilC) [Legionella fallonii LLAP-10]
MAKSRDLVLTFHYEGVNKTGQKIAGDIQARSLAIAKADLRKQGIIANKVIKKRKSFFDRKNKKITSGDITVFSRQLATMI
ESGIPLVQSFDIVAKGQTNNKLKNLLETVKRDIETGLTLSESLIKHPAYFNQLFCNLVDAGEKSGSLDTMLNKVATYKEK
IETIKKKIKKALTYPIAVLVVALIVTAGLLIFVVPQFESLFKGFGADLPALTQAVVDMSKFFQAYWYLIFGSLGAALYAF
IYAKKHSLNFAQNLDRSLLKFPVIGTILQKAAIARFSRTLSITFAAGLPLVEALKSVSGATGNIIYAKATERIREEVSTG
QQLYTSMENTHLFPNMVVQMVAIGEESGALEKMLGKVADFYEEEVDNAVDALSSLLEPIIMSILGVLVGGLVIAMYLPIF
KLGQAI

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1113614 LFA_RS06985 WP_045095547.1 1722393..1723613(+) (pilC) [Legionella fallonii LLAP-10]
ATGGCCAAAAGTAGAGATTTAGTTTTAACTTTTCACTATGAGGGAGTCAATAAAACTGGCCAAAAAATAGCTGGAGATAT
TCAGGCTAGAAGTCTTGCTATAGCAAAAGCTGACTTACGTAAGCAAGGAATTATTGCTAATAAAGTTATCAAAAAAAGAA
AGTCCTTTTTTGACAGAAAAAACAAGAAAATTACGTCCGGAGATATCACTGTTTTTAGTCGTCAACTGGCCACAATGATC
GAATCTGGCATTCCATTGGTACAATCTTTTGATATTGTAGCTAAAGGACAAACTAACAATAAATTAAAAAATCTGCTAGA
AACAGTTAAACGAGATATTGAAACTGGATTAACGCTATCAGAGTCGTTAATAAAACATCCCGCTTATTTTAATCAATTAT
TTTGTAATCTTGTTGATGCCGGTGAAAAATCTGGCTCACTTGACACCATGTTGAACAAAGTTGCCACCTATAAGGAAAAA
ATTGAAACAATAAAAAAGAAAATCAAGAAAGCACTGACCTACCCCATTGCGGTGCTTGTAGTCGCTCTTATAGTAACAGC
AGGCCTACTTATCTTTGTTGTGCCGCAATTTGAGTCTTTATTTAAAGGATTTGGGGCTGATTTACCTGCCTTAACCCAAG
CCGTAGTCGATATGTCAAAATTCTTCCAAGCTTATTGGTACCTCATATTTGGCTCATTAGGAGCGGCACTTTATGCCTTT
ATTTATGCCAAAAAACATTCATTGAATTTTGCTCAAAACCTCGATAGGTCATTATTAAAATTTCCTGTCATCGGAACCAT
ATTACAAAAAGCAGCTATTGCTCGTTTTAGTAGAACGTTATCCATTACATTTGCTGCAGGCTTACCTTTAGTTGAGGCGT
TAAAATCAGTATCAGGAGCTACAGGAAACATTATTTATGCCAAAGCTACAGAAAGAATTAGAGAAGAGGTCTCCACAGGA
CAACAGCTCTACACTTCAATGGAAAATACGCATTTATTTCCTAATATGGTAGTTCAAATGGTCGCAATTGGTGAAGAATC
AGGCGCTCTAGAAAAGATGCTAGGTAAAGTGGCTGATTTTTATGAAGAAGAAGTCGATAATGCTGTAGATGCACTAAGCA
GTTTATTAGAACCAATAATTATGTCAATATTAGGTGTTTTGGTAGGTGGATTGGTTATTGCGATGTATTTACCTATATTC
AAACTTGGCCAAGCCATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098G4Q3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

82.02

100

0.82
  pilC Acinetobacter baumannii D1279779

54.074

99.754

0.539
  pilC Pseudomonas stutzeri DSM 10701

55.051

97.537

0.537
  pilC Acinetobacter baylyi ADP1

52.709

100

0.527
  pilG Neisseria meningitidis 44/76-A

45.592

97.783

0.446
  pilG Neisseria gonorrhoeae MS11

45.34

97.783

0.443
  pilC Vibrio cholerae strain A1552

42.602

96.552

0.411
  pilC Vibrio campbellii strain DS40M4

41.582

96.552

0.401
  pilC Thermus thermophilus HB27

35.507

100

0.362

Multiple sequence alignment