Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   HMPREF9319_RS00385 Genome accession   NZ_GL397128
Coordinates   69143..70084 (+) Length   313 a.a.
NCBI ID   WP_003062917.1    Uniprot ID   A0AAW6YGD8
Organism   Streptococcus equinus ATCC 700338     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 64143..75084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS00375 (HMPREF9319_0068) rpoC 64906..68544 (+) 3639 WP_003062914.1 DNA-directed RNA polymerase subunit beta' -
  HMPREF9319_RS00380 (HMPREF9319_0069) - 68710..69072 (+) 363 WP_003062916.1 DUF1033 family protein -
  HMPREF9319_RS00385 (HMPREF9319_0070) comYA 69143..70084 (+) 942 WP_003062917.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF9319_RS00390 (HMPREF9319_0071) comYB 70008..71051 (+) 1044 WP_003062919.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF9319_RS00395 (HMPREF9319_0072) comYC 71051..71344 (+) 294 WP_003062921.1 competence type IV pilus major pilin ComGC Machinery gene
  HMPREF9319_RS00400 (HMPREF9319_0073) comYD 71328..71759 (+) 432 WP_003062922.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF9319_RS00405 (HMPREF9319_0074) comGE 71713..72006 (+) 294 WP_080543606.1 competence type IV pilus minor pilin ComGE -
  HMPREF9319_RS00410 (HMPREF9319_0075) comYF 71990..72427 (+) 438 WP_041974065.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF9319_RS00415 (HMPREF9319_0076) comYG 72399..72731 (+) 333 WP_003062925.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF9319_RS00420 (HMPREF9319_0077) comYH 72786..73757 (+) 972 WP_003062926.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF9319_RS00425 (HMPREF9319_0078) - 73795..74994 (+) 1200 WP_003062927.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35829.96 Da        Isoelectric Point: 5.0613

>NTDB_id=1111659 HMPREF9319_RS00385 WP_003062917.1 69143..70084(+) (comYA) [Streptococcus equinus ATCC 700338]
MIQEEAKQLIKDAVEVNAQDIYILPREDCYEVYQRVGDQRRFVDYFEIEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPDK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVVRASLTGAIVFSTIHAKSIPGV
YERLLELGVSKQELENSLRAIVYQRLIGGGGVIDFVKENFESHRPECWNAKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1111659 HMPREF9319_RS00385 WP_003062917.1 69143..70084(+) (comYA) [Streptococcus equinus ATCC 700338]
ATGATTCAGGAAGAAGCAAAGCAACTCATTAAAGATGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGATTGTTATGAAGTGTATCAACGCGTAGGAGACCAACGGCGATTTGTTGATTATTTTGAGATAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGTGAGAAACGTCGCAGTCAGTTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGCTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGCCGTCATGACTTGCAATATTGGTTTGATGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGAC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTGATAAG
CAAGTCATTACAATTGAGGACCCTGTTGAAATCAAACAAGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGATGAGCTAATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATTGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTCGTTCGTGCAAGTTTGACAGGAGCTATTGTGTTTTCGACCATTCATGCGAAAAGTATCCCTGGCGTT
TACGAACGTCTTTTGGAATTGGGTGTTAGTAAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGTGGAGGAGGTGTGATTGATTTTGTTAAAGAAAACTTTGAAAGTCACCGACCAGAATGCTGGAATGCAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.489

99.361

0.681
  comYA Streptococcus mutans UA140

68.167

99.361

0.677
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.774

99.042

0.661
  comYA Streptococcus gordonii str. Challis substr. CH1

66.238

99.361

0.658
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

63.462

99.681

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.821

99.681

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

53.994

100

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

41.901

90.735

0.38

Multiple sequence alignment