Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ACGHT2_RS00740 Genome accession   NZ_AP031455
Coordinates   109768..110709 (+) Length   313 a.a.
NCBI ID   WP_003062917.1    Uniprot ID   A0AAW6YGD8
Organism   Streptococcus pasteurianus strain k46-0107-A9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 104768..115709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGHT2_RS00730 (K460107A9_00920) rpoC 105531..109169 (+) 3639 WP_003062914.1 DNA-directed RNA polymerase subunit beta' -
  ACGHT2_RS00735 (K460107A9_00930) - 109335..109697 (+) 363 WP_058692629.1 DUF1033 family protein -
  ACGHT2_RS00740 (K460107A9_00940) comYA 109768..110709 (+) 942 WP_003062917.1 competence type IV pilus ATPase ComGA Machinery gene
  ACGHT2_RS00745 (K460107A9_00950) comYB 110633..111676 (+) 1044 WP_003062919.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACGHT2_RS00750 (K460107A9_00960) comYC 111676..111969 (+) 294 WP_003062921.1 competence type IV pilus major pilin ComGC Machinery gene
  ACGHT2_RS00755 (K460107A9_00970) comYD 111953..112384 (+) 432 WP_058692630.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACGHT2_RS00760 (K460107A9_00980) comGE 112338..112631 (+) 294 WP_081048608.1 competence type IV pilus minor pilin ComGE -
  ACGHT2_RS00765 (K460107A9_00990) comYF 112585..113052 (+) 468 WP_058692632.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACGHT2_RS00770 (K460107A9_01000) comYG 113006..113356 (+) 351 WP_238374707.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACGHT2_RS00775 (K460107A9_01010) comYH 113411..114382 (+) 972 WP_117479470.1 class I SAM-dependent methyltransferase Machinery gene
  ACGHT2_RS00780 (K460107A9_01020) - 114420..115619 (+) 1200 WP_058692635.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35829.96 Da        Isoelectric Point: 5.0613

>NTDB_id=109585 ACGHT2_RS00740 WP_003062917.1 109768..110709(+) (comYA) [Streptococcus pasteurianus strain k46-0107-A9]
MIQEEAKQLIKDAVEVNAQDIYILPREDCYEVYQRVGDQRRFVDYFEIEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPDK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVVRASLTGAIVFSTIHAKSIPGV
YERLLELGVSKQELENSLRAIVYQRLIGGGGVIDFVKENFESHRPECWNAKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=109585 ACGHT2_RS00740 WP_003062917.1 109768..110709(+) (comYA) [Streptococcus pasteurianus strain k46-0107-A9]
ATGATTCAGGAAGAAGCAAAGCAACTCATTAAAGATGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGATTGTTATGAAGTGTATCAACGCGTAGGAGACCAACGGCGATTTGTTGATTATTTTGAGATAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGTGAGAAACGTCGCAGTCAGTTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGCTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGCCGTCATGACTTGCAATATTGGTTTGATGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGAC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTGATAAG
CAAGTCATTACAATTGAGGACCCTGTTGAAATCAAACAAGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGATGAGCTAATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATTGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTCGTTCGTGCAAGTTTGACAGGAGCTATTGTGTTTTCGACCATTCATGCGAAAAGTATCCCTGGCGTT
TACGAACGTCTTTTGGAATTGGGTGTTAGTAAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGTGGAGGAGGTGTGATTGATTTTGTTAAAGAAAACTTTGAAAGTCACCGACCAGAATGCTGGAATGCAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.489

99.361

0.681
  comYA Streptococcus mutans UA140

68.167

99.361

0.677
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.774

99.042

0.661
  comYA Streptococcus gordonii str. Challis substr. CH1

66.238

99.361

0.658
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

63.462

99.681

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.821

99.681

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

53.994

100

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

41.901

90.735

0.38

Multiple sequence alignment